The centre is located at the Henry Wellcome Building of Genomic Medicine, which cost £20 million and was officially opened in June 2000 with Anthony Monaco as the director.[2][3]
Within the WHG a number of 'cores' provide services to the researchers:
Oxford Genomics Centre
The Oxford Genomics Centre provides high throughput sequencing services, using Illumina HiSeq4000 2500 and NextSeq500 and MiSeq.[4] They also offer Oxford Nanopore MinION and PromethION sequencing.[4] There are also Array platforms for genotyping, gene expression, and methylation including Illuminia Infinium, Affymetrix and Fluidigm.[5]
Research Computing Core
The Research Computing Core provides access to computer resources including 4120 cores and 4.2 PB of storage.[6]
Transgenics
The Transgenics Core provides access to genetically modified mice and cell lines.[7]
The WHG has been involved in many international statistical genetics advances including the Wellcome Trust Case Control Consortia (WTCCC, WTCCC2), the 1000 Genomes Project and the International HapMap Project.[9]
^Ramagopalan, S. V. (2008). "Life on top—working@ the Wellcome Trust Centre for Human Genetics: Scotland Yard for DNA detectives". New Biotechnology. 25 (1): 39–45. doi:10.1016/j.nbt.2008.04.007. PMID18504015.
