Some of these may be signed. There may be differences near cities or in other limited areas, where the U.S. Highway takes the bypass and the State Road doesn't (for instance).
- SR 5
- US 1, Key West to Jacksonville
- US 17, Jacksonville to Georgia
- SR 7
- US 441, Miami to Royal Palm Beach
- Continues north separate for a bit
- SR 8
- I-10, Alabama to Jacksonville
- SR 8A
- SR 9
- Separate in Miami
- I-95, Miami to Georgia
- SR 9A
- SR 10
- US 90, Alabama to Jacksonville
- Separate east of Jacksonville
- SR 15
- US 441, Belle Glade to Ashton
- Separate, Ashton to Orlando
- US 17, Orlando to Jacksonville
- US 1/US 23, Jacksonville to Georgia
- SR 20
- Separate, Niceville to Tallahassee
- US 27, Tallahassee to High Springs
- Separate, High Springs
- US 441, High Springs to Gainesville
- Separate, Gainesville to Palatka
- US 17, Palatka to East Palatka
- Separate, East Palatka to Bunnell
- SR 25
- US 27, Miami to Lady Lake
- Separate, Lady Lake to Belleview
- US 441, Belleview to High Springs
- US 41, High Springs to Georgia
- SR 30
- SR 35
- US 17, Punta Gorda to Bartow
- US 98, Bartow to Dade City
- US 301, Dade City to Belleview
- Separate, Belleview to Silver Springs
- SR 39
- Separate, Keentown to Zephyrhills
- US 301, Zephyrhills to Dade City
- SR 41
- SR 43
- SR 45
- US 41, Naples to Tampa
- Separate, Tampa
- US 41, Tampa to High Springs
- SR 47
- US 129, Chiefland to Trenton
- Separate, Trenton to Lake City
- US 441, Lake City to Georgia
- SR 49
- US 129, Trenton to Branford
- Separate, Branford to Live Oak
- SR 51
- Separate, Steinhatchee to Live Oak
- US 129, Live Oak to Jasper
- SR 55
- SR 57
- SR 61
- US 319, Medart to Crawfordville
- Separate, Crawfordville to Tallahassee
- US 319, Tallahassee to Georgia
- SR 63
- US 27, Tallahassee to Georgia
- SR 75
- US 231, Panama City to Alabama
- SR 80
- Separate, Fort Myers to Belle Glade
- US 441, Belle Glade to Royal Palm Beach
- US 98, Royal Palm Beach to West Palm Beach
- SR 83
- US 331, Santa Rosa Beach to De Funiak Springs
- Separate, De Funiak Springs to Alabama
- SR 90
- SR 91
- SR 93
- I-75, Miami to Palmetto
- I-275, Palmetto to Lutz
- I-75, Lutz to Georgia
- SR 93A
- SR 95
- US 29, Pensacola to Alabama
- SR 100
- US 129, Georgia to Jasper
- US 41, Jasper to Lake City
- US 90, Lake City to Newco
- Separate, Newco to Palatka
- US 17, Palatka to East Palatka
- Separate, East Palatka to Flagler Beach
- SR 112
- I-195; continues west separate
- SR 187
- US 331, De Funiak Springs to Alabama
- SR 200
- Separate, Hernando to Ocala
- US 301, Ocala to Callahan
- Separate, Callahan to Fernandina Beach
- SR 212
- US 90, Jacksonville to Jacksonville Beach
- SR 249
- US 129, Branford to Live Oak
- Separate from Live Oak to Jasper
- SR 261
- SR 263
- US 319, south of Tallahassee
- Separate, west of Tallahassee
- SR 369
- US 319, Crawfordville to Tallahassee
- SR 375
- US 319, Medart to Sopchoppy
- Separate, Sopchoppy to Bloxham
- SR 377
- US 319, east of Carabelle to Sopchoppy
- SR 400
- I-4, Tampa to Daytona Beach
- Continues east separate for a bit
- SR 500
- SR 530
- US 192, southeast of Clermont to Kissimmee
- Separate east of Kissimmee
- SR 555
- US 17, Bartow to Lake Alfred
- SR 595
- SR 600
- US 92, St. Petersburg to Daytona Beach
- SR 683
- SR 700
- US 98, West Palm Beach to Wellington
- Separate, Wellington to Canal Point
- US 98, Canal Point to Brooksville
- Separate in portions of Brooksville
- US 98, Brooksville to Chassahowitzka
- SR 821
- SR 836
- I-395; continues west separate
- SR 862