The Zee Cine Award Best Actor in a Comic Role is chosen by a jury organized by Zee Entertainment Enterprises, and the winner is announced at the ceremony.
| Wins | Recipient |
|---|---|
| 2 | Govinda, Paresh Rawal, Riteish Deshmukh, Arshad Warsi, Kartik Aaryan |
| Year | Winner | Film |
|---|---|---|
| 1998 | Kamal Haasan | Chachi 420 |
| 1999 | Govinda | Bade Miyan Chote Miyan |
| 2000 | Haseena Maan Jaayegi | |
| 2001 | Paresh Rawal | Hera Pheri |
| 2002 | Johnny Lever | Love Ke Liye Kuchh Bhi Karega |
| 2003 | Paresh Rawal | Awara Paagal Deewana |
| 2004 | Arshad Warsi | Munnabhai M.B.B.S. |
| 2005 | Riteish Deshmukh | Masti |
| 2006 | Bluffmaster! | |
| 2007 | Arshad Warsi | Lage Raho Munna Bhai |
| 2008 | Vinay Pathak | Bheja Fry |
| 2009 | Not Held | |
| 2010 | Not Held | |
| 2011 | Boman Irani | Well Done Abba |
| 2012 | Divyendu Sharma | Pyaar Ka Punchnama |
| 2013 | Abhishek Bachchan | Bol Bachchan |
| 2014 | Varun Sharma | Fukrey |
| 2016 | Nawazuddin Siddiqui | Bajrangi Bhaijaan |
| 2017 | Rishi Kapoor | Kapoor & Sons |
| 2019 | Kartik Aaryan | Sonu Ke Titu Ki Sweety |
| 2020 | Diljit Dosanjh and Kartik Aaryan | Good Newwz and Pati Patni Aur Woh |
| 2021 | Not Held | |
| 2022 | Not Held | |
| 2023 | Maniesh Paul | Jugjugg Jeeyo |
| 2024 | Ayushmann Khuranna | Dream Girl 2 |