Zinterol
Zinterol.png
Names
IUPAC name
N-[5-[2-[(1,1-dimethyl-2-phenylethyl)amino]-1-hydroxyethyl]-2-hydroxyphenyl]methanesulfonamide
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.189.867 Edit this at Wikidata
MeSH Zinterol
UNII
  • InChI=1S/C19H26N2O4S/c1-19(2,12-14-7-5-4-6-8-14)20-13-18(23)15-9-10-17(22)16(11-15)21-26(3,24)25/h4-11,18,20-23H,12-13H2,1-3H3 checkY
    Key: XJBCFFLVLOPYBV-UHFFFAOYSA-N checkY
  • InChI=1/C19H26N2O4S/c1-19(2,12-14-7-5-4-6-8-14)20-13-18(23)15-9-10-17(22)16(11-15)21-26(3,24)25/h4-11,18,20-23H,12-13H2,1-3H3
    Key: XJBCFFLVLOPYBV-UHFFFAOYAI
  • O=S(=O)(Nc1cc(ccc1O)C(O)CNC(C)(C)Cc2ccccc2)C
Properties
C19H26N2O4S
Molar mass 378.49 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Zinterol is a beta-adrenergic agonist.[1]

Its structure is based on soterenol (antiarrhythmic) and phentermine.

References

  1. ^ Heubach JF, Graf EM, Molenaar P, et al. (May 2001). "Murine ventricular L-type Ca2+ current is enhanced by zinterol via β1-adrenoceptors, and is reduced in TG4 mice overexpressing the human β2-adrenoceptor". Br. J. Pharmacol. 133 (1): 73–82. doi:10.1038/sj.bjp.0704045. PMC 1572761. PMID 11325796.