Formula Satu musim 1981 merupakan musim balapan reguler Formula Satu yang diadakan dari tanggal 15 Maret sampai dengan tanggal 17 Oktober 1981, dengan memperlombakan 15 lomba. Tampil sebagai juara dunia adalah pembalap asal Brasil, yaitu Nelson Piquet.

Skuat tim dan pembalap

Peserta	Konstruktor	Sasis	Mesin	Ban	No	Pembalap	Ronde	Pembalap tes
Albilad Williams Racing Team TAG Williams Racing Team	Williams	FW07C FW07D	Ford Cosworth DFV 3.0 V8	M G	1	Alan Jones	All
					2	Carlos Reutemann	All
Tyrrell Racing Team	Tyrrell	010 011	Ford Cosworth DFV 3.0 V8	M A	3	Eddie Cheever	All
					4	Kevin Cogan	1
						Ricardo Zunino	2-3
						Michele Alboreto	4-15
Parmalat Racing Team	Brabham	BT49C BT50	Ford Cosworth DFV 3.0 V8	M G	5	Nelson Piquet	All
					6	Hector Rebaque	All
Marlboro McLaren International	McLaren	M29F MP4/1	Ford Cosworth DFV 3.0 V8	M	7	John Watson	All
					8	Andrea de Cesaris	All
Team ATS	ATS	D4 D5	Ford Cosworth DFV 3.0 V8	M A	9	Jan Lammers	1-4
						Slim Borgudd	5-15
					10	Slim Borgudd	4
Team Essex Lotus John Player Team Lotus	Lotus	81B 87 88 88B	Ford Cosworth DFV 3.0 V8	M G	11	Elio de Angelis	1-3, 5-15
					12	Nigel Mansell	1-3, 5-15
Ensign Racing	Ensign	N180B	Ford Cosworth DFV 3.0 V8	M A	14	Marc Surer	1-6
						Ricardo Londoño	2
						Eliseo Salazar	7-15
Equipe Renault Elf	Renault	RS20B RS30	Renault-Gordini EF1 1.5 V6t	M	15	Alain Prost	All
					16	René Arnoux	All
March Grand Prix Team	March	811	Ford Cosworth DFV 3.0 V8	M A	17	Derek Daly	1-3, 7-15
						Eliseo Salazar	4-6
					18	Eliseo Salazar	1-3
						Derek Daly	4-6
Fittipaldi Automotive	Fittipaldi	F8C	Ford Cosworth DFV 3.0 V8	M A P	20	Keke Rosberg	1-10, 12-15
					21	Chico Serra	1-10, 12-15
Marlboro Team Alfa Romeo	Alfa Romeo	179B 179C 179D	Alfa Romeo 1260 3.0 V12	M	22	Mario Andretti	All
					23	Bruno Giacomelli	All
Equipe Talbot Gitanes	Ligier	JS17	Matra MS81 3.0 V12	M	25	Jean-Pierre Jarier	1-2
						Jean-Pierre Jabouille	3-7
						Patrick Tambay	8-15
					26	Jacques Laffite	All
Scuderia Ferrari SpA SEFAC	Ferrari	126CK	Ferrari 021 1.5 V6t	M	27	Gilles Villeneuve	All
					28	Didier Pironi	All
Ragno Arrows Beta Racing Team	Arrows	A3	Ford Cosworth DFV 3.0 V8	M P	29	Riccardo Patrese	All
					30	Siegfried Stohr	1-13
						Jacques Villeneuve, Sr.	14-15
Osella Squadra Corse	Osella	FA1B FA1C	Ford Cosworth DFV 3.0 V8	M	31	Miguel Ángel Guerra	1-4
						Piercarlo Ghinzani	5
						Beppe Gabbiani	6-15
					32	Beppe Gabbiani	1-5
						Piercarlo Ghinzani	6
						Giorgio Francia	7
						Miguel Ángel Guerra	8
						Jean-Pierre Jarier	9-15
Theodore Racing Team	Theodore	TY01	Ford Cosworth DFV 3.0 V8	M A	33	Patrick Tambay	1-7
						Marc Surer	8-15
Candy Toleman Motorsport	Toleman	TG181	Hart 415T 1.5 L4t	P	35	Brian Henton	4-15
					36	Derek Warwick	4-15

Pranala luar

• 1981 F1 review Diarsipkan 2010-12-27 di Wayback Machine.