Results of the ISCD 2010 study ranking the levels of damage caused by drugs, in the opinion of drug-harm experts. When harm to self and others is summed, alcohol was the most harmful of all drugs considered, scoring 72%.

Alcoholic lung disease is disease of the lungs caused by excessive alcohol consumption. The term 'alcoholic lung disease' is not a generally accepted medical diagnosis, and "the association between alcohol abuse and acute lung injury...remains largely unrecognized, even by lung researchers". [1]

Chronic alcohol ingestion impairs multiple critical cellular functions in the lung. These cellular impairments lead to increased susceptibility to serious complications from lung disease. Recent research cites alcoholic lung disease as comparable to liver disease in alcohol-related mortality.[2] Alcoholics have a higher risk of developing acute respiratory distress syndrome (ARDS) and experience higher rates of mortality from ARDS when compared to non-alcoholics.

The mechanisms of alcoholic lung disease are:

These chemical changes compound the negative mechanical and microbiological effects of alcoholism on the respiratory system. These include: impaired gag reflex and cilia function and greater likelihood of colonies of pneumococcal bacteria in the upper respiratory system.

Research on potential treatments for Alcoholic Lung Disease are ongoing.

References

  1. ^ Kershaw CD, Guidot DM (2008). "Alcoholic Lung Disease". Alcohol Research and Health. 31 (1): 66–75.
  2. ^ Kershaw CD, Guidot DM (2008). "Alcoholic Lung Disease". Alcohol Research and Health. 31 (1): 66–75.
  3. ^ Joshi PC, Guidot DM (2007). "The alcoholic lung: epidemiology, pathophysiology, and potential therapies". Am. J. Physiol. Lung Cell Mol. Physiol. 292 (4): L813–23. doi:10.1152/ajplung.00348.2006. PMID 17220370. ((cite journal)): Unknown parameter |month= ignored (help)