British physician scientist
(Robert) Charles Swanton FRS FMedSci FRCP is British physician scientist specialising in oncology and cancer research . Swanton is a senior group leader at London's Francis Crick Institute ,[3] Royal Society Napier Professor in Cancer[4] and thoracic medical oncologist at University College London [5] and University College London Hospitals,[6] [7] co-director of the Cancer Research UK (CRUK) Lung Cancer Centre of Excellence, and Chief Clinician of Cancer Research UK.[8] [9]
Education
Swanton completed was educated at St Paul's School, London [2] and completed his PhD in 1999[10] at what was then the Imperial Cancer Research Fund Laboratories (now the Francis Crick Institute) and his Cancer Research UK clinician scientist/medical oncology training in 2008.[7]
Research and career
Professor Swanton speaking at a conference in 2015 Swanton combines his laboratory research with clinical duties as co-director of the CRUK Lung Cancer Centre, focussed on how tumours evolve over space and time.[7] He has helped to define the branched evolutionary histories of solid tumours, processes that drive cancer cell-to-cell variation in the form of new cancer mutations or chromosomal instabilities, and the impact of such cancer diversity on effective immune surveillance and clinical outcome.[1] [7] [11] [12]
Swanton is a co-founder of Achilles Therapeutics[13] with Sergio Quezada, Karl Peggs and Mark Lowdell. Achilles Therapeutics is a UCL/CRUK and Francis Crick Institute[14] biotechnology company funded by Syncona[15] that develops adoptive T cell therapies targeting clonal/truncal neo-antigens present in every tumour cell to limit drug resistance and tumour evolution.[citation needed ]
Awards and honours
Personal life
Swanton is the son of Robert Howard Swanton (MD, FRCP) a consultant cardiologist at UCL.[23]
^ a b Charles Swanton publications indexed by Google Scholar
^ a b c Anon (2017). "Swanton, Prof. (Robert) Charles" . Who's Who (online Oxford University Press ed.). Oxford: A & C Black. doi :10.1093/ww/9780199540884.013.U286524 . (Subscription or UK public library membership required.)
^ "Charles Swanton – The Francis Crick Institute" . crick.ac.uk .
^ Anon (2016). "Leading scientists awarded Royal Society Research Professorships" . royalsociety.org . Royal Society . Retrieved 27 November 2018 .
^ "Iris View Profile" . iris.ucl.ac.uk . Archived from the original on 22 May 2017. Retrieved 12 January 2022 .
^ "The UCLH lung cancer service" . uclh.nhs.uk . Retrieved 27 November 2018 .
^ a b c d e f Anon (2018). "Professor Charles Swanton FMedSci FRS" . London: Royal Society . One or more of the preceding sentences incorporates text from the royalsociety.org website where: "All text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License ." --"Terms, conditions and policies | Royal Society" . Archived from the original on 11 November 2016. Retrieved 27 June 2018 .((cite web ))
: CS1 maint: bot: original URL status unknown (link )
^ "Chief Executive and Executive Board" . 27 September 2013.
^ Charles Swanton publications from Europe PubMed Central
^ Swanton, Robert Charles (1998). Viral cyclin disruption of mammalian cell cycle control mechanisms . london.ac.uk (PhD thesis). University College London (University of London). OCLC 941060556 . EThOS uk.bl.ethos.286205 .
^ Swanton, Charles; Mann, David J.; Fleckenstein, Bernhard; Neipel, Frank; Peters, Gordon; Jones, Nic (1997). "Herpes viral cyclin/Cdk6 complexes evade inhibition by CDK inhibitor proteins". Nature . 390 (6656): 184–187. Bibcode :1997Natur.390..184S . doi :10.1038/36606 . ISSN 0028-0836 . PMID 9367157 . S2CID 4397584 .
^ Charles Swanton publications indexed by the Scopus bibliographic database. (subscription required)
^ "Our Team – Achilles Therapeutics" . achillestx.com . Retrieved 27 November 2018 .
^ UCL (5 October 2016). "UCL spin-out Achilles Therapeutics to develop immunotherapies for cancer" . UCL News . Retrieved 27 November 2018 .
^ "Achilles Therapeutics" . Syncona . Retrieved 27 November 2018 .
^ "Pontecorvo Prize for best PhD thesis" . cancerresearchuk.org . 28 October 2015. Retrieved 27 November 2018 .
^ "Professor Charles Swanton – The Academy of Medical Sciences" . acmedsci.ac.uk . Retrieved 27 November 2018 .
^ Systems, eZ. "List of Award Winners / Fondazione San Salvatore" . fondazionesansalvatore.ch . Archived from the original on 22 July 2018. Retrieved 27 November 2018 .
^ "Translational Cancer Research Prize" . cancerresearchuk.org . 28 October 2015. Retrieved 27 November 2018 .
^ Jukic, Igor. "EMBO welcomes 65 new members" . Embo.org . Archived from the original on 27 September 2017. Retrieved 27 November 2018 .
^ "Kraft Prize Symposium – Massachusetts General Hospital, Boston, MA" . massgeneral.org . Retrieved 27 November 2018 .
^ Azvolinsky, Anna (2018). "Cancer Evolutionist: A Profile of Charles Swanton" . The Scientist .
^ Anon (2017). "Swanton, Robert Howard" . Who's Who (online Oxford University Press ed.). Oxford: A & C Black. doi :10.1093/ww/9780199540884.013.U4000216 . (Subscription or UK public library membership required.)
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