Clinical data | |
---|---|
Other names | 4-(diphenylmethoxy)-1-methyl-piperidine |
AHFS/Drugs.com | International Drug Names |
Routes of administration | Oral, Topical |
ATC code | |
Legal status | |
Legal status |
|
Pharmacokinetic data | |
Elimination half-life | 24–40 hours[1] |
Identifiers | |
| |
CAS Number |
|
PubChem CID | |
IUPHAR/BPS | |
DrugBank |
|
ChemSpider |
|
UNII | |
KEGG |
|
ChEBI | |
ChEMBL | |
CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.005.170 |
Chemical and physical data | |
Formula | C19H23NO |
Molar mass | 281.399 g·mol−1 |
3D model (JSmol) | |
| |
| |
(verify) |
Diphenylpyraline (DPP; sold as Allergen, Arbid, Belfene, Diafen, Hispril, Histyn, Lergobine, Lyssipol, Mepiben, Neargal) is a first-generation antihistamine with anticholinergic effects of the diphenylpiperidine class.[2][3][4] It is marketed in Europe for the treatment of allergies.[2][3][5] DPP has also been found to act as a dopamine reuptake inhibitor and produces hyperactivity in rodents.[6] It has been shown to be useful in the treatment of Parkinsonism.[7]
Benzimidazoles (*) | |
---|---|
Diarylmethanes |
|
Ethylenediamines | |
Tricyclics | |
Others |
|
For topical use |
Dopaminergics |
| ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Anticholinergics | |||||||||||
Others | |||||||||||
|
D1-like |
| ||||||
---|---|---|---|---|---|---|---|
D2-like |
| ||||||
DATTooltip Dopamine transporter (DRIsTooltip Dopamine reuptake inhibitors) |
| ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NETTooltip Norepinephrine transporter (NRIsTooltip Norepinephrine reuptake inhibitors) |
| ||||||||||||||
SERTTooltip Serotonin transporter (SRIsTooltip Serotonin reuptake inhibitors) |
| ||||||||||||||
VMATsTooltip Vesicular monoamine transporters |
| ||||||||||||||
Others |
| ||||||||||||||