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Clinical data | |
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ECHA InfoCard | 100.107.752 ![]() |
Chemical and physical data | |
Formula | C11H23N |
Molar mass | 169.312 g·mol−1 |
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Neramexane is a drug related to memantine,[1] which acts as an NMDA antagonist[2] and has neuroprotective effects.[3] It is being developed for various possible applications, including treatment of tinnitus,[4][5] Alzheimer's disease,[6] drug addiction[7] and as an analgesic.[8] Animal studies have also suggested antidepressant[9] and nootropic[10] actions, so there are a wide range of potential applications this drug may be used for. It also acts as a nicotinic acetylcholine receptor antagonist.[11]
A clinical trial found that doses of 50 mg and above safely improved tinnitus scores over 16 weeks.[12]
AMPARTooltip α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor |
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KARTooltip Kainate receptor |
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NMDARTooltip N-Methyl-D-aspartate receptor |
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nAChRsTooltip Nicotinic acetylcholine receptors |
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