AL-LAD

Legal status
Legal status	UK: Class A Illegal in Denmark, Sweden and Switzerland
Identifiers
IUPAC name (6aR,9R)-N,N-diethyl-7-prop-2-enyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide
CAS Number	65527-61-9 N
PubChem CID	15227511
ChemSpider	21106248 Y
UNII	020O2SR91L
ChEMBL	ChEMBL281787 Y
CompTox Dashboard (EPA)	DTXSID30215822
Chemical and physical data
Formula	C22H27N3O
Molar mass	349.4713 g/mol g·mol−1
3D model (JSmol)	Interactive image
SMILES CCN(CC)C(=O)[C@@H]2/C=C1/c3cccc4ncc(C[C@H]1N(C2)CC=C)c34
InChI InChI=1S/C22H27N3O/c1-4-10-25-14-16(22(26)24(5-2)6-3)11-18-17-8-7-9-19-21(17)15(13-23-19)12-20(18)25/h4,7-9,11,13,16,20,23H,1,5-6,10,12,14H2,2-3H3/t16-,20-/m1/s1 Y Key:JCQLEPDZFXGHHQ-OXQOHEQNSA-N Y
NY (what is this?)  (verify)

AL-LAD, also known as 6-allyl-6-nor-LSD, is a psychedelic drug and an analog of lysergic acid diethylamide (LSD).^[1] It is described by Alexander Shulgin in the book TiHKAL (Tryptamines i Have Known And Loved). It is synthesized starting from LSD as a precursor, using allyl bromide as a reactant.

While AL-LAD has subtly different effects than LSD, and appears to be slightly shorter lasting, their potencies are similar;^[2][3] an active dose of AL-LAD is reported to be between 50 and 150 micrograms.^[4] AL-LAD has a known but short and highly uncommon history of recreational human use, which originated in Ireland and the UK, but spread internationally.

AL-LAD does not cause a color change with the Marquis, Mecke or Mandelin reagents,^[5] but does cause the Ehrlich's reagent to turn purple because of the presence of the indole moiety in its structure.

AL-LAD is not scheduled by the United Nations' Convention on Psychotropic Substances.^[6]

AL-LAD is illegal in Denmark.^[7]

AL-LAD is possibly illegal in Latvia. Although it isn't specifically scheduled, it may be controlled as an LSD structural analog due to an amendment made on June 1, 2015.^[8]

The Riksdag added AL-LAD to Narcotic Drugs Punishments Act under swedish schedule I ("substances, plant materials and fungi which normally do not have medical use" ) as of January 26, 2016, published by Medical Products Agency (MPA) in regulation HSLF-FS 2015:35 listed as 6-allyl-6-nor-LSD, AL-LAD, and 6-allyl-N,N-dietyl-9,10-didehydroergolin-8-karboxamid.^[9]

AL-LAD is illegal in Switzerland.^[10]

AL-LAD is illegal in the UK. On June 10, 2014 the UK Advisory Council on the Misuse of Drugs (ACMD) recommended that AL-LAD be specifically named in the UK Misuse of Drugs Act as a class A drug despite not identifying any harm associated with its use.^[11] The UK Home office accepted this advice and announced a ban of the substance to be enacted on 6 January 2015 as part of The Misuse of Drugs Act 1971 (Amendment) (No. 2) Order 2014.

AL-LAD is not scheduled as a controlled substance at the federal level in the United States,^[12] but AL-LAD could legally be considered an analog of LSD, in which case, sales or possession with intent for human consumption could be prosecuted under the Federal Analogue Act.^[13]

• 1P-LSD
• ETH-LAD
• PRO-LAD
• LSZ

• Watts, V. J.; Mailman, R. B.; Lawler, C. P.; Neve, K. A.; Nichols, D. E. (1995). "LSD and structural analogs: Pharmacological evaluation at D1 dopamine receptors". Psychopharmacology. 118 (4): 401–9. doi:10.1007/BF02245940. PMID 7568626.
• Niwaguchi, T; Nakahara, Y; Ishii, H (1976). "Studies on lysergic acid diethylamide and related compounds. IV. Syntheses of various amide derivatives of norlysergic acid and related compounds". Yakugaku Zasshi. 96 (5): 673–8. PMID 987200.
• Robert C. Pfaff, Xuemei Huang, Danuta Marona-Lewicka, Robert Oberlender and David E. Nichols: Lysergamides Revisited. In: NIDA Research Monograph 146: Hallucinogens: An Update. p. 52, 1994, United States Department of Health and Human Services.

• AL-LAD entry in TiHKAL
• AL-LAD entry in TiHKAL • info
• AL-LAD Thread at UKChemicalResearch.org

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