The Winnipeg Blue Bombers were once again permitted to challenge for the Grey Cup following a rule dispute a year earlier. In a meeting of the previous two Grey Cup champions, the Blue Bombers prevailed, sending the coveted mug west for the third time.
Final regular season standings
Note: GP = Games Played, W = Wins, L = Losses, T = Ties, PF = Points For, PA = Points Against, Pts = Points
- Bold text means that they have clinched the playoffs.
1941 Western All-Stars
NOTE: During this time most players played both ways, so the All-Star selections do not distinguish between some offensive and defensive positions.
- QB – Art Stevenson, Winnipeg Blue Bombers
- FW – Ken Charlton, Regina Roughriders
- HB – Fritz Hanson, Winnipeg Blue Bombers
- HB – Jim Ladner, Winnipeg Blue Bombers
- FB – Dan Capraru, Regina Roughriders
- E – Larry Haynes, Vancouver Grizzlies
- E – Ches McCance, Winnipeg Blue Bombers
- C – Mel Wilson, Winnipeg Blue Bombers
- G – Maurice Williams, Regina Roughriders
- G – Les Lear, Winnipeg Blue Bombers
- T – Gord Gellhaye, Vancouver Grizzlies
- T – Lou Mogul, Winnipeg Blue Bombers