1981 U.S. Clay Court Championships
Date	August 3–9
Edition	13th
Draw	64S / 32D (M) 56S / 32D (W)
Prize money	$380,000
Surface	Clay / outdoor
Location	Indianapolis, US
Champions
Men's singles
José Luis Clerc[1]
Women's singles
Andrea Jaeger
Men's doubles
Kevin Curren / Steve Denton[2]
Women's doubles
JoAnne Russell / Virginia Ruzici
← 1980 · U.S. Clay Court Championships · 1982 →

The 1981 U.S. Clay Court Championships was a men's Grand Prix and women's Toyota Series tennis tournament held in Indianapolis in the United States and played on outdoor clay courts. It was the 13th edition of the tournament and was held from August 3 through August 9, 1981. Second-seeded José Luis Clerc and top-seeded Andrea Jaeger won the singles titles.^[3]

Finals

Men's singles

José Luis Clerc defeated Ivan Lendl 4–6, 6–4, 6–2

• It was Clerc's 6th title of the year and the 16th of his career.

Women's singles

Andrea Jaeger defeated Virginia Ruzici 6–1, 6–0

• It was Jaeger's 3rd title of the year and the 7th of her career.

Men's doubles

Kevin Curren / Steve Denton defeated Raúl Ramírez / Van Winitsky 6–3, 5–7, 7–5

• It was Curren's 2nd title of the year and the 5th of his career. It was Denton's 2nd title of the year and the 6th of his career.

Women's doubles

JoAnne Russell / Virginia Ruzici defeated Sue Barker / Paula Smith 6–2, 6–2

• It was Russell's 1st title of the year and the 2nd of her career. It was Ruzici's 1st title of the year and the 12th of her career.