The 2010 edition of the Vuelta Mexico Telmex was won by Óscar Sevilla of Rock Racing Team.
| Year | Winner | Nationality | Team |
|---|---|---|---|
Overall Leader 
|
Óscar Sevilla |  Spain
|
Rock Racing |
Combativity Leader 
|
Florencio Ramos |  Mexico
|
Chiapas Tequila Afamado |
Mountain Leader 
|
Rodolfo Torres |  Colombia
|
Boyacá Orgullo Nacional |
Best Mexican 
|
Ignacio Sarabia | Mexico
|
Rock Racing |
u23 leader 
|
Jose Ramon Aguirre | Mexico
|
Canel's Turbo |
Amore & Vita Conad Arenas Tlaxcala Bocaya Orgullo de América Canel's Turbo
CKT Champion System Empacadora San Marcos ISD Neri Orven PRODEG CEDAJ Guanajuato Rock Racing Selección Chiapas Tequila Afamado
Selección Cuba
Selección Guatemala
Selección Venezuela
Spider Tech by Planet Energy
Team Concordia Forsikring
Team Kuota Indeland
Team Raleigh
Team Type One Veracruz| Stage | Date | Course | Distance | Type | Winner | |
|---|---|---|---|---|---|---|
| 1 | April 17 |  Aldo Ilesic
| ||||
| 2 | April 18 | Veracruz–Xalapa | 108 |  |
Medium-mountain stage | François Parisien
|
| 3 | April 19 | Xalapa–Orizaba | 173 | Ignacio Sarabia
| ||
| 4 | April 20 | Orizaba–Tlaxcala | 220 | Luis F. Macías
| ||
| 5 | April 21 | Tlaxcala–Cuautla | 175 | Flavio de Luna
| ||
| 6 | April 23 | Cuernavaca–Metepec | 180 |  |
Mountain stage | Ignacio Sarabia
|
| 7 | April 24 | Ajusco | 11 |  |
Individual time trial | Rodolfo Torres
|
| 8 | April 25 | Reforma Circuit | 100 |  |
Flat stage | Philip Nielsen
|
| Rank | Rider | Team | Time |
|---|---|---|---|
|
|
Óscar Sevilla (ESP)
|
Rock Racing | 26h 34 18" |
| 2 | José Rincón (COL)
|
Boyacá Orgullo de America | + 13" |
| 3 | Gregorio Ladino (COL)
|
Boyacá Orgullo de America | + 18" |
| 4 | Víctor Niño (COL)
|
Orven | + 45" |
| 5 | Ignacio Sarabia (MEX)
|
Rock Racing | + 46" |