Protein-coding gene in the species Homo sapiens
A4GALT |
---|
|
Identifiers |
---|
Aliases | A4GALT, A14GALT, A4GALT1, Gb3S, P(k), P1, P1PK, PK, alpha 1,4-galactosyltransferase, alpha 1,4-galactosyltransferase (P blood group) |
---|
External IDs | OMIM: 607922 MGI: 3512453 HomoloGene: 9690 GeneCards: A4GALT |
---|
EC number | 2.4.1.228 |
---|
|
|
|
|
|
Wikidata |
|
Lactosylceramide 4-alpha-galactosyltransferase is an enzyme that in humans is encoded by the A4GALT gene.[5][6]
The protein encoded by this gene catalyzes the transfer of galactose to lactosylceramide to form globotriaosylceramide, which has been identified as the P(k) antigen of the P blood group system. The encoded protein, which is a type II membrane protein found in the Golgi, is also required for the synthesis of the bacterial verotoxins receptor.[6]