Protein found in humans
COL25A1 |
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Identifiers |
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Aliases | COL25A1, AMY, CLAC, CLAC-P, CLACP, CFEOM5, Collagen, type XXV, alpha 1, collagen type XXV alpha 1, collagen type XXV alpha 1 chain |
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External IDs | OMIM: 610004 MGI: 1924268 HomoloGene: 57111 GeneCards: COL25A1 |
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Wikidata |
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Collagen alpha-1(XXV) chain is a protein that in humans is encoded by the COL25A1 gene.[5][6]
COL25A1 is a brain-specific membrane-bound collagen. Proteolytic processing releases CLAC, a soluble form of COL25A1 containing the extracellular collagen domains that associates with senile plaques in Alzheimer disease (AD; MIM 104300) brains (Osada et al., 2005).[supplied by OMIM][6]
Interactions
Collagen, type XXV, alpha 1 has been shown to interact with Amyloid precursor protein.[5]