|Preferred IUPAC name
3D model (JSmol)
CompTox Dashboard (EPA)
|Molar mass||45.085 g·mol−1|
|Density||649.6 kg m−3 (at 25 °C)|
|Melting point||−93.00 °C; −135.40 °F; 180.15 K|
|Boiling point||7 to 9 °C; 44 to 48 °F; 280 to 282 K|
|1.540 kg L−1|
|Vapor pressure||170.3 kPa (at 20 °C)|
|310 μmol Pa−1 kg−1|
Std enthalpy of
|−21 to −17 kJ mol−1|
|H220, H302, H315, H318, H332, H335|
|P210, P261, P280, P305+P351+P338|
|NFPA 704 (fire diamond)|
|Flash point||−6 °C (21 °F; 267 K) (liquid)|
|401 °C (754 °F; 674 K)|
|Lethal dose or concentration (LD, LC):|
LD50 (median dose)
|698 mg/kg (rat, oral)|
316 mg/kg (mouse, oral)
240 mg/kg (rabbit, oral)
240 mg/kg (guinea pig, oral)
LC50 (median concentration)
|4700 ppm (rat, 4 hr)|
4540 ppm (rat, 6 hr)
7650 ppm (mouse, 2 hr)
|NIOSH (US health exposure limits):|
|TWA 10 ppm (18 mg/m3)|
|TWA 10 ppm (18 mg/m3)|
IDLH (Immediate danger)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
what is ?)(
Dimethylamine is an organic compound with the formula (CH3)2NH. This secondary amine is a colorless, flammable gas with an ammonia-like odor. Dimethylamine is commonly encountered commercially as a solution in water at concentrations up to around 40%. An estimated 270,000 tons were produced in 2005.
The molecule consists of a nitrogen atom with two methyl substituents and one proton. Dimethylamine is a weak base and the pKa of the ammonium CH3-NH+
2-CH3 is 10.73, a value above methylamine (10.64) and trimethylamine (9.79).
Dimethylamine reacts with acids to form salts, such as dimethylamine hydrochloride, an odorless white solid with a melting point of 171.5 °C. Dimethylamine is produced by catalytic reaction of methanol and ammonia at elevated temperatures and high pressure:
Dimethylamine is found quite widely distributed in animals and plants, and is present in many foods at the level of a few mg/kg.
Dimethylamine is a precursor to several industrially significant compounds. It reacts with carbon disulfide to give dimethyl dithiocarbamate, a precursor to zinc bis(dimethyldithiocarbamate) and other chemicals used in the sulfur vulcanization of rubber. The solvents dimethylformamide and dimethylacetamide are derived from dimethylamine. It is raw material for the production of many agrichemicals and pharmaceuticals, such as dimefox and diphenhydramine, respectively. The chemical weapon tabun is derived from dimethylamine. The surfactant lauryl dimethylamine oxide is found in soaps and cleaning compounds. Unsymmetrical dimethylhydrazine, a rocket fuel, is prepared from dimethylamine.
It is basic, in both the Lewis and Brønsted senses. It easily forms dimethylammonium salts upon treatment with acids. Deprotonation of dimethylamine can be effected with organolithium compounds. The resulting LiNMe2, which adopts a cluster-like structure, serves as a source of "Me2N−". This lithium amide has been used to prepare volatile metal complexes such as tetrakis(dimethylamido)titanium and pentakis(dimethylamido)tantalum.
It is also a Lewis base.
It reacts with many carbonyl compounds. Aldehydes give aminals. For example reaction of dimethylamine and formaldehyde gives bis(dimethylamino)methane:
It converts esters to dimethylamides.
Dimethylamine undergoes nitrosation to give dimethylnitrosamine, a carcinogen.
It is an attractant for boll weevils.
Dimethylamine is not very toxic with the following LD50 values: 736 mg/kg (mouse, i.p.); 316 mg/kg (mouse, p.o.); 698 mg/kg (rat, p.o.); 3900 mg/kg (rat, dermal); 240 mg/kg (guinea pig or rabbit, p.o.).