Monoclonal antibody | |
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Type | Whole antibody |
Source | Humanized (from mouse) |
Target | interferon gamma |
Clinical data | |
ATC code |
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Identifiers | |
CAS Number | |
ChemSpider |
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UNII | |
KEGG |
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Chemical and physical data | |
Molar mass | ca. 150 kg/mol |
NY (what is this?) (verify) |
Fontolizumab (planned trade name HuZAF) is a humanized monoclonal antibody[1] and an immunosuppressive drug for the treatment of auto-immune diseases like Crohn's disease.[2] A phase II clinical trial investigating the use for rheumatoid arthritis was terminated because the first phase did not meet the endpoint.[3]
Intracellular (initiation) |
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Intracellular (reception) |
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Extracellular |
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Unsorted |
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Chemokine |
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CSF |
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Interferon |
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Interleukin |
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TGFβ |
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TNF |
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Others |
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