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Trade names | Eovist |
Other names | Gadoxetate disodium (USAN US) |
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Formula | C23H30GdN3O11 |
Molar mass | 681.75 g·mol−1 |
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Gadoxetic acid is a gadolinium-based MRI contrast agent.[3] Its salt, gadoxetate disodium, is marketed as Primovist in Europe and Eovist in the United States by Bayer HealthCare Pharmaceuticals.[1][4]
It is used to increase the T1 signal intensity while imaging the liver lesions such as benign cysts, haemangioma, and liver cancer. It is excreted into bile by active secretion.[5]
In those with end-stage renal failure, the clearance rate is only 17% with terminal half-life of 12 times longer than those with normal renal function.[5]