|No. 45 Hamilton Tiger-Cats|
|Born:||July 5, 1994|
|Height||6 ft 2 in (188 cm)|
|Weight||233 lb (106 kg)|
|2017–2018||Winnipeg Blue Bombers|
Jovan Santos-Knox (born July 5, 1994) is a professional Canadian football linebacker for the Hamilton Tiger-Cats of the Canadian Football League (CFL). He played college football for the UMass Minutemen.
Santos-Knox was signed by the Winnipeg Blue Bombers after driving nine hours with his father to a tryout camp which his father had found in Charlotte, North Carolina. He started his rookie season on special teams but by the end of the regular season was a starting linebacker and was being praised by coach Mike O'Shea and media for big plays at big moments of games. After recording 10 tackles and 3 sacks against Toronto on July 27, 2018, Santos-Knox was named the CFL's third star of the week.
Santos-Knox spent the 2019 season with the Edmonton Eskimos where he played in three regular season games. After the CFL canceled the 2020 season due to the COVID-19 pandemic, he chose to opt-out of his contract with the Edmonton Eskimos on August 27, 2020.
On February 6, 2021, it was announced that Santos-Knox had signed with the Hamilton Tiger-Cats.