The community lies within one mile of the Missouri-Kansas state line. It is on Missouri Route D between Drexel to the south and West Line to the north. Coldwater Creek lies to the south and east and its tributary, Cave Spring Creek, is to the north.[3]
History
Lisle was platted in 1892, taking the name of J. D. Lisle, the original owner of the town site.[4] A post office called Lisle was established in 1891, and remained in operation until 1954.[5]