Protein-coding gene in the species Homo sapiens
PDE6D |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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1KSG, 1KSH, 1KSJ, 3T5G, 3T5I, 4JHP, 4JV6, 4JV8, 4JVB, 4JVF, 5E8F, 5E80, 5F2U |
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Identifiers |
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Aliases | PDE6D, JBTS22, PDED, phosphodiesterase 6D |
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External IDs | OMIM: 602676 MGI: 1270843 HomoloGene: 1954 GeneCards: PDE6D |
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EC number | 3.1.4.35 |
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Wikidata |
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Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta is an enzyme that in humans is encoded by the PDE6D gene.[5][6][7] PDE6D was originally identified as a fourth subunit of rod cell-specific cGMP phosphodiesterase (PDE) (EC 3.1.4.35). The precise function of PDE delta subunit in the rod specific GMP-PDE complex is unclear. In addition, PDE delta subunit is not confined to photoreceptor cells but is widely distributed in different tissues. PDE delta subunit is thought to be a specific soluble transport factor for certain prenylated proteins and Arl2-GTP a regulator of PDE-mediated transport.[8]