Poison ivy
Poison ivy fall coloration
Poison ivy fall coloration
Scientific classificationEdit this classification
Kingdom: Plantae
Clade: Tracheophytes
Clade: Angiosperms
Clade: Eudicots
Clade: Rosids
Order: Sapindales
Family: Anacardiaceae
Subfamily: Anacardioideae
Genus: Toxicodendron

T. orientale Greene
T. radicans (L.) Kuntze
T. rydbergii (Small ex Rydb.) Greene

This article duplicates the scope of other articles, specifically Toxicodendron radicans. Please discuss this issue and help introduce a summary style to the article. (March 2023)

Poison ivy is a type of allergenic plant in the genus Toxicodendron native to Asia and North America. Formerly considered a single species, Toxicodendron radicans, poison ivies are now generally treated as a complex of three separate species: Toxicodendron radicans, Toxicodendron rydbergii, and Toxicodendron orientale. They are well known for causing urushiol-induced contact dermatitis, an itchy, irritating, and sometimes painful rash, in most people who touch them. The rash is caused by urushiol, a clear liquid compound in the plant's sap. They are variable in appearance and habit, and despite its common name, it is not a "true" ivy (Hedera), but rather a member of the cashew and pistachio family (Anacardiaceae). T. radicans is commonly eaten by many animals, and the seeds are consumed by birds, but poison ivy is most often thought of as an unwelcome weed.


Three species of poison ivy are generally recognised; they are sometimes considered subspecies of Toxicodendron radicans:[1][2][3]


Poison ivies can grow as small plants, shrubs, or climbing vines.[4] They are commonly characterized by clusters of leaves, each containing three leaflets,[4] hence the common expression "leaves of three, let it be".[5] These leaves can vary between an elliptic to egg shape and will have either smooth, lobed, or toothed margins. Additionally, the leaf clusters are alternate on the stem. Clusters of small, greenish flowers bloom from May to July and produce white berries in the fall a few millimeters in diameter.[6]

Health effects

A video describing the effects of poison ivy on the body
Blisters from contact with poison ivy

Main article: Urushiol-induced contact dermatitis

Urushiol-induced contact dermatitis is the allergic reaction caused by poison ivy. In extreme cases, a reaction can progress to anaphylaxis. Around 15 to 25 percent of people have no allergic reaction to urushiol, but most people have a greater reaction with repeated or more concentrated exposure.[7][8]

Over 350,000 people are affected by urushiol annually in the United States.[9]

The oozing fluids released by scratching blisters do not spread the poison. The fluid in the blisters is produced by the body and it is not urushiol itself.[10] The appearance of a spreading rash indicates that some areas received more of the poison and reacted sooner than other areas or that contamination is still occurring from contact with objects to which the original poison was spread.[citation needed]

Those affected can unknowingly spread the urushiol inside the house, on phones, door knobs, couches, counters, desks, and so on, thus in fact repeatedly coming into contact with poison ivy and extending the length of time of the rash. If this happens, the surfaces should be wiped with bleach or a commercial urushiol removal agent. The blisters and oozing result from blood vessels that develop gaps and leak fluid through the skin; if the skin is cooled, the vessels constrict and leak less.[11] If plant material with urushiol is burned and the smoke then inhaled, this rash will appear on the lining of the lungs, causing extreme pain and possibly fatal respiratory difficulty.[10] If poison ivy is eaten, the mucus lining of the mouth and digestive tract can be damaged.[12]

Urushiol oil can remain active for several years, so handling dead leaves or vines can cause a reaction. In addition, oil transferred from the plant to other objects (such as pet fur) can cause the rash if it comes into contact with the skin.[13][10] Clothing, tools, and other objects that have been exposed to oil should be washed to prevent further reactions.[14]


Main article: Urushiol-induced contact dermatitis § Treatments

Immediate washing with soap and cold water or rubbing alcohol may help prevent a reaction.[15] During a reaction, calamine lotion or diphenhydramine may help mitigate symptoms. Corticosteroids, either applied to the skin or taken by mouth, may be appropriate in extreme cases. An astringent containing aluminum acetate (such as Burow's solution) may also provide relief and soothe the uncomfortable symptoms of the rash.[16]

Urushiol binds to the skin on contact where it causes severe itching that develops into reddish inflammation or uncoloured bumps, and then blistering. These lesions may be treated with calamine lotion, Burow's solution compresses, dedicated commercial poison ivy itch creams, or baths to relieve discomfort,[17] though recent studies have shown some traditional medicines to be ineffective.[18][19] Over-the-counter products to ease itching—or simply oatmeal baths and baking soda—are now recommended by dermatologists for the treatment of poison ivy.[20]

A plant-based remedy cited to counter urushiol-induced contact dermatitis is jewelweed, though jewelweed extracts had no positive effect in clinical studies.[21][22][23][24] Others argue that prevention of lesions is easy if one practices effective washing, using plain soap, scrubbing with a washcloth, and rinsing three times within 2–8 hours of exposure.[25]

The pentadecyl catechols of the oleoresin within the sap of poison ivy and related plants causes the allergic reaction; the plants produce a mixture of pentadecylcatechols, which collectively is called urushiol. After injury, the sap leaks to the surface of the plant where the urushiol becomes a blackish lacquer after contact with oxygen.[26][27]


Typically, the rash from the urushiol oil lasts about five to twelve days, but in extreme cases it can last a month or more.[28] A urushiol rash usually develops within a week of exposure and can last 1–4 weeks, depending on severity and treatment. In rare cases, urushiol reactions may require hospitalization.[10]

Related species

People who are sensitive to urushiol can also experience a similar rash from mangoes. Mangoes are in the same family (Anacardiaceae) as poison ivy; the sap of the mango tree and skin of mangoes has a chemical compound similar to urushiol.[29] A related allergenic compound is present in the raw shells of cashews.[30] Similar reactions have been reported occasionally from contact with the related fragrant sumac (Rhus aromatica) and Japanese lacquer tree. These other plants are also in the family Anacardiaceae.[citation needed]

Similar allergenic plants


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  2. ^ "Toxicodendron orientale". Plants of the World Online. Royal Botanic Gardens, Kew. Retrieved 19 October 2020.
  3. ^ "Toxicodendron radicans". Plants of the World Online. Royal Botanic Gardens, Kew. Retrieved 19 October 2020.
  4. ^ a b c d e Innes, Robin J. (2012). "Toxicodendron radicans, T. rydbergii". Fire Effects Information System (FEIS). US Department of Agriculture (USDA), Forest Service (USFS), Rocky Mountain Research Station, Fire Sciences Laboratory.
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