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Small subunit ribosomal ribonucleic acid (SSU rRNA) is the smaller of the two major RNA components of the ribosome. Associated with a number of ribosomal proteins, the SSU rRNA forms the small subunit of the ribosome. It is encoded by SSU-rDNA.

Other data
PDB structuresPDBe


Characteristics of the SSU rRNA for exemplary species.
Type SSU rRNA size Species Length Accession Reference
Bacterial (Prokaryotic) 16S Escherichia coli 1,541 nt J01859.1 [1]
Archaeal (Prokaryotic) 16S Halobacterium salinarum 1,473 nt M38280.1 [2]
Eukaryotic 18S Homo sapiens 1,969 nt M10098.1 [3]
Mitochondrial 12S Homo sapiens 954 nt NC_012920.1 [4][5]
Plastid 16S Arabidopsis thaliana 1,491 nt NC_000932.1 [6]

Use in phylogenetics

SSU rRNA sequences are widely used for determining evolutionary relationships among organisms, since they are of ancient origin and are found in all known forms of life.[7]

See also


  1. ^ "Escherichia coli 16S ribosomal RNA". 13 June 2017.
  2. ^ "Halobacterium salinarum 16S ribosomal RNA". 7 August 1991.
  3. ^ "Homo sapiens 18S ribosomal RNA (nuclear)". 2 May 1986.
  4. ^ Homo sapiens mitochondrion, complete genome. "Revised Cambridge Reference Sequence (rCRS): accession NC_012920", National Center for Biotechnology Information. Retrieved on 20 February 2017.
  5. ^ Anderson S, Bankier AT, Barrell BG, de Bruijn MH, Coulson AR, Drouin J, et al. (April 1981). "Sequence and organization of the human mitochondrial genome". Nature. 290 (5806): 457–465. Bibcode:1981Natur.290..457A. doi:10.1038/290457a0. PMID 7219534. S2CID 4355527.
  6. ^ "Arabidopsis thaliana 16S ribosomal RNA (chloroplast)". 26 September 2019.
  7. ^ Woese CR, Kandler O, Wheelis ML (June 1990). "Towards a natural system of organisms: proposal for the domains Archaea, Bacteria, and Eucarya". Proceedings of the National Academy of Sciences of the United States of America. 87 (12): 4576–4579. Bibcode:1990PNAS...87.4576W. doi:10.1073/pnas.87.12.4576. PMC 54159. PMID 2112744.