Hepatocellular carcinoma was one of the Natural sciences good articles, but it has been removed from the list. There are suggestions below for improving the article to meet the good article criteria. Once these issues have been addressed, the article can be renominated. Editors may also seek a reassessment of the decision if they believe there was a mistake. | |||||||||||||
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This article is or was the subject of a Wiki Education Foundation-supported course assignment. Further details are available on the course page. Student editor(s): Asifur1996.
Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 22:18, 17 January 2022 (UTC)
This article is or was the subject of a Wiki Education Foundation-supported course assignment. Further details are available on the course page. Student editor(s): Jules014.
Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 23:21, 16 January 2022 (UTC)
In hepatocellular carcinoma , there is high level of serum copper and copper to zinc ratio as the serum zinc level is low.Is this interesting to measure the serum copper and zinc level?
Since liver cancer is not synonym for hepatocellular carcinoma, I turned liver cancer, which was previously a redirect to here, to a disambiguation page. --Steven Fruitsmaak 12:50, 22 May 2006 (UTC)
Also, I think the translations should be different, not translating "liver cancer" but "hepatocellular carcinoma". --Steven Fruitsmaak 17:25, 25 May 2006 (UTC)
Please redirect from HCC.
>(an alternative name may be hepatoma) This was originally mentioned after the name. However, hepatomas are generally benign and harmless, which cannot be said about HCC Jfdwolff 00:05, 27 Feb 2004 (UTC)
Hepatoma is an old name for primary hepatocellular carcinoma. [Yes, it's a misnomer.] Axl 18:18, 3 Jan 2005 (UTC)
So what do you call benign liver neoplasms, if not hepatoma? JFW | T@lk 16:04, 5 Jan 2005 (UTC)
Good, it must be my training abroad that's leading to the confusion :-) JFW | T@lk 21:11, 6 Jan 2005 (UTC)
it is called HepatoCellular Carcinoma means malignant tumor of epithelial tissue (liver spicificlly) but hepatoma means a benign tumor of hepatocytes!!!
Is Aspergillus responsible for a "unique" type of HCC ? I wasn't aware of there being a big difference between the two forms, and also leaves us with the problem of what to do with those who have both Hep B and Aflatoxin (e.g. in West Africa) MattW 12:35, 26 July, 2005
Is this interesting to measure serum copper and Cu/Zn ratio in HCC?
Dear Jfdwolff -- I think we need to revise the treatment section, or perhaps add a research heading, where we could link to clinical trials and current research -- the reason is that this may help patients -- What do you think? Anita Brenner
JFW: Your reverts eliminated my references to screening tests, Dr. So's genetics research, even reference sites for patients and this week's ASCO abstracts.
I see by the history that you have reverted every time some one wanders in and posts a new link. All the links I have seen in the history, the ones that you erase, appear to be valid resources.
You describe yourself as a physician, so I don't understand why you want to deprive patients of full access to the vast array of online resources, particularly when they may be of more benefit than the outdated summary you keep reverting to.
What's the problem?
Anita Brenner
What Wikipedia needs is a well-written clear outline, not just of frontline research but of basic principles such as staging, histology and prognosis. That's very nice: are you actually going to do this or just remove anyone else's contributions? And since you've set yourself up as a veteran here, perhaps you ought to reacquaint yourself with Don't bite the newcomers and lose the supercilious attitude. --Calton | Talk 14:47, 16 May 2005 (UTC)
Ciao, JfdWolff, You win.
17 May 2005 Anita Brenner
Does anyone object against this article (Franca AV, Elias Junior J, Lima BL, Martinelli AL, Carrilho FJ. Diagnosis, staging and treatment of hepatocellular carcinoma. Braz J Med Biol Res 2004;37:1689-705. PMID 15517086) as a background review? JFW | T@lk 15:50, 16 May 2005 (UTC)
I found a lot of content removed in this edit, by an anon with one edit. I've restored the lost content, but there have been some minor changes made since then that are now lost. I think this is the proper action, but if anyone disagrees, let me know. --Arcadian 01:51, 29 January 2006 (UTC)
Incidence in Europe and USA doi:10.1111/j.1572-0241.2007.01337.x JFW | T@lk 07:21, 7 August 2007 (UTC)
Anybody who does not know that hepatoma is the same as hepatocellular carcinoma should NOT contribute to this article !!!81.244.197.160 (talk) 20:44, 28 March 2008 (UTC)
Study that lacks solid conclusions (from abstract at least) about HCC in the USA. Risk is higher in particular ethnic groups, which probably reflects the fact that they have risk factors. doi:10.1016/j.amjmed.2008.03.005 JFW | T@lk 11:21, 21 May 2008 (UTC)
Just curious, but why haven't epidermal growth factors been mentioned in this article? I recently read an article in JAMA (DOI 10.1001/jama.2007.65) of relationship between a single nucleotide polymorphism on the EGF gene and the risk for developing HCC in patients with cirrhosis. Another article (PMID 7862454) from 1995 determined that the overexpression of secreted EGF fusion protein led to the development of HCC in transgenic mice. I think this new research is worth mentioning in the "Future directions" section of the article. Nishkid64 (Make articles, not wikidrama) 20:46, 17 September 2008 (UTC)
Needs extensive work to add inline references and reorganization to fulfill GA criteria. The treatment section is currently just a bunch of bullet points. Needs to be wikified. No verification for the people who had this condition. Could also do with a expanded classification section.--Doc James (talk · contribs · email) 03:20, 31 May 2009 (UTC)
Considering that this page is likely to be read by patients and their families trying to understand hepatoma and how it can be treated, the section on treatment needs considerable work to update it and correct a number of errors. For example, the article states that cryosurgery is "a new technique" - when in fact it has existed for decades and has been widely used to treat hepatoma since the 1980s. In the case of hepatoma it is also associated with high-risk to patients from shock, which can arise as a result of hormone and enzyme cascades triggered by the therapy. On the other hand, radiofrequency ablation as a treatment for hepatoma is relatively new (in widepsread use less than 7 years) and considered favorable to cryosurgery as it is minimally invasive, less risky and easier to perform (negligible risk of harmful biochemical response). The discussion of TACE is also incorrect - it states that TACE is not suitable for treatment of large tumors >8cm; this figure should be revised to >15cm, as it is now commonly used and frequently succeeds for tumors up to that size, without concurrent PEI or other treatments. Anyway, some update is certainly needed. Mudpuddles1418 (talk) 22:46, 23 June 2009 (UTC)
This section is hugely skewed towards locally-directed liver therapies. Need to organize better (curative vs palliative intentions), more written on surgery/transplant, with more updated information on TACE/radioembolization and the other local therapies. Dr G (talk) 21:18, 9 July 2017 (UTC)
i suggest merging hepatocellular carcinoma into the liver cancer article for two reasons:1 this article does not cite any refrences,needs updating,wikification,and cleanup.and 2 hcc is the main type of liver cancer.24.97.164.250 (talk) 16:47, 9 December 2009 (UTC)
i agree.for a fairly common and very important malignancy,this article is a mess.there is outdated information like"a new therapy sorafenib is showing some promise in clinical trials".currently,sorafenib is the standered of care in advanced hepatocellular carcinoma (incorrectly termed hepatoma above).the treatment section esp needs cleanup and updating.i think that if in a few months the article is not at least somewhat improved,the whole article will need to be merged into liver cancer.169.244.148.235 (talk) 15:52, 4 January 2010 (UTC)
I think the Liver Cancer article is redundant. There is a Liver Tumour article which includes information about Benign and Malignant Tumours and then each separate tumour type should have its own article (if noteworthy). The Liver Cancer article does not have any useful or new information in it that cannot be placed under liver tumour or HCC. Natasqi (talk) 06:48, 16 February 2010 (UTC)
==Society and culture==
Awareness[edit]
The Jade Ribbon Campaign is used for awareness of liver cancer and hepatitis B in the Pacific Islands, where such illnesses are more widespread than elsewhere.
Famous people[edit]
- Johannes Brahms famous late Romantic German composer. Died April 3, 1897 of liver cancer.
- Morihei Ueshiba founder of the Japanese martial art of aikido. Died in 1969 of hepatocellular carcinoma.
- John Coltrane Jazz musician. Died in 1967 from liver cancer.
- Jim Hutton Died in 1979 from liver cancer.
- Mickey Mantle Hall of Fame Baseball player with the New York Yankees.
- Chris LeDoux Country Music Hall of Fame legend, and former Pro Rodeo rider.
- Munetaka Higuchi Drummer for Japanese heavy metal band Loudness, died in 2008 of hepatocellular carcinoma.
- Mick Ronson British Rock'n'Roll guitarist who died in 1993 of hepatocellular carcinoma.
- Erich Honecker former leader of East Germany who died in 1994 in exile.
- Ray Charles famous recording soulful music artist, Rock And Roll Hall of Fame, died on June 10, 2004.
- Sun Yat-sen Father of the Nation in mainland China and in Taiwan
- Édith Piaf French singer and cultural icon who "is almost universally regarded as France's greatest popular singer.", died on 10 or 11 October 1963.
- Gregory Hines Professional dancer, film actor, and choreographer. Died in August 2003 of liver cancer.
- Dave Thomas Founder of Wendys, died in 2002 of liver cancer.
- Joan Finney Governor of Kansas (1991–1995) died of liver cancer in 2001
- Robin Gibb Musician, member of the Bee Gees. Died of liver cancer in 2012[1]
Doc James (talk · contribs · email) 01:19, 23 December 2011 (UTC)
In the Diagnosis section of the article it mentions that a biopsy to confirm the diagnosis is not required if certain imaging criteria are met. What are the criteria? Nonagonal Spider (talk) 06:24, 9 January 2012 (UTC)
Seminar doi:10.1016/S0140-6736(11)61347-0 JFW | T@lk 20:26, 29 April 2012 (UTC)
Gut doi:10.1136/gutjnl-2014-307990 JFW | T@lk 14:20, 6 April 2015 (UTC)
doi:10.7326/M14-2509 - MRI is most sensitive, CT/MRI are better than USS. JFW | T@lk 15:41, 19 May 2015 (UTC)
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doi:10.1053/j.gastro.2015.12.041 JFW | T@lk 10:16, 31 March 2016 (UTC)
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Metabolic syndrome and NASH [first mention] are also increasingly recognized as risk factors for HCC.