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{| class="wikitable sortable mw-collapsible (({state<includeonly>|mw-collapsed</includeonly>))}" style="margin-left: auto; margin-right: auto; border: none;"
|+ class="nowrap" | ((Navbar|Relative affinities of first-generation nonsteroidal antiandrogens for the androgen receptor|mini=y)) Relative affinities of <noinclude>[[Nonsteroidal antiandrogen#First-generation|first-generation]]</noinclude><includeonly>first-generation</includeonly> <noinclude>[[nonsteroidal antiandrogen]]s</noinclude><includeonly>nonsteroidal antiandrogens</includeonly> for the <noinclude>[[androgen receptor]]</noinclude><includeonly>androgen receptor</includeonly>
|-
! rowspan="2" | Species !! colspan="3" | ((abbrlink|IC<sub>50</sub>|Half maximal inhibitory concentration)) (nM) !! colspan="3" | ((abbrlink|RBA|Relative binding affinity)) (ratio)
|-
! [[Bicalutamide]] !! [[2-Hydroxyflutamide]] !! [[Nilutamide]] !! ((Abbr|Bica|Bicalutamide)) / ((Abbr|2-OH-flu|2-hydroxyflutamide)) !! ((Abbr|Bica|Bicalutamide)) / ((Abbr|nilu|nilutamide)) !! Ref
|-
| Rat || 190 || 700 || ((abbr|ND|No data)) || 4.0 || ((abbr|ND|No data)) || <ref name="pmid3625091">((cite journal | vauthors = Furr BJ, Valcaccia B, Curry B, Woodburn JR, Chesterson G, Tucker H | title = ICI 176,334: a novel non-steroidal, peripherally selective antiandrogen | journal = The Journal of Endocrinology | volume = 113 | issue = 3 | pages = R7–R9 | date = June 1987 | pmid = 3625091 | doi = 10.1677/joe.0.113R007 ))</ref>
|-
| Rat || ~400 || ~900 || ~900 || 2.3 || 2.3 || <ref name="pmid8136296Receptor">((cite journal | vauthors = Teutsch G, Goubet F, Battmann T, Bonfils A, Bouchoux F, Cerede E, Gofflo D, Gaillard-Kelly M, Philibert D | display-authors = 6 | title = Non-steroidal antiandrogens: synthesis and biological profile of high-affinity ligands for the androgen receptor | journal = The Journal of Steroid Biochemistry and Molecular Biology | volume = 48 | issue = 1 | pages = 111–119 | date = January 1994 | pmid = 8136296 | doi = 10.1016/0960-0760(94)90257-7 | s2cid = 31404295 ))</ref>
|-
| Rat || ((abbr|ND|No data)) || ((abbr|ND|No data)) || ((abbr|ND|No data)) || 3.3 || ((abbr|ND|No data)) || <ref name="pmid2615358">((cite journal | vauthors = Winneker RC, Wagner MM, Batzold FH | title = Studies on the mechanism of action of Win 49596: a steroidal androgen receptor antagonist | journal = Journal of Steroid Biochemistry | volume = 33 | issue = 6 | pages = 1133–1138 | date = December 1989 | pmid = 2615358 | doi = 10.1016/0022-4731(89)90420-2 ))</ref>
|-
| Rat<sup>a</sup> || 3595 || 4565 || 18620 || 1.3 || 5.2 || <ref name="LuoMartel1996">((cite journal| vauthors = Luo S, Martel C, Leblanc G, Candas B, Singh SM, Labrie C, Simard J, Bélanger A, Labrie F | display-authors = 6 |title=Relative potencies of Flutamide and Casodex: preclinical studies|journal=Endocrine Related Cancer|volume=3|issue=3|year=1996|pages=229–241|issn=1351-0088|doi=10.1677/erc.0.0030229))</ref>
|-
| Human || ~300 || ~700 || ~500 || 2.5 || 1.6 || <ref name="Ayub_1989">((cite journal | vauthors = Ayub M, Levell MJ | title = The effect of ketoconazole related imidazole drugs and antiandrogens on [3H] R 1881 binding to the prostatic androgen receptor and [3H]5 alpha-dihydrotestosterone and [3H]cortisol binding to plasma proteins | journal = Journal of Steroid Biochemistry | volume = 33 | issue = 2 | pages = 251–255 | date = August 1989 | pmid = 2788775 | doi = 10.1016/0022-4731(89)90301-4 ))</ref>
|-
| Human || ~100 || ~300 || ((abbr|ND|No data)) || ~3.0 || ((abbr|ND|No data)) || <ref name="pmid8693644">((cite journal | vauthors = Kemppainen JA, Wilson EM | title = Agonist and antagonist activities of hydroxyflutamide and Casodex relate to androgen receptor stabilization | journal = Urology | volume = 48 | issue = 1 | pages = 157–163 | date = July 1996 | pmid = 8693644 | doi = 10.1016/S0090-4295(96)00117-3 ))</ref>
|-
| Human<sup>a</sup> || 2490 || 2345 || 5300 || 1.0 || 2.1 || <ref name="LuoMartel1996" />
|- class="sortbottom"
| colspan="7" style="width: 1px; background-color:#eaecf0; text-align: center;" | '''Footnotes:''' <sup>a</sup> = Controversial data. '''Sources:''' <noinclude><ref name="pmid12496872">((cite journal | vauthors = Kolvenbag GJ, Furr BJ, Blackledge GR | title = Receptor affinity and potency of non-steroidal antiandrogens: translation of preclinical findings into clinical activity | journal = Prostate Cancer and Prostatic Diseases | volume = 1 | issue = 6 | pages = 307–314 | date = December 1998 | pmid = 12496872 | doi = 10.1038/sj.pcan.4500262 | s2cid = 33497597 ))</ref><ref name="WirthAltwein1998">((cite book| vauthors = Furr BJ | chapter = Antiandrogen binding to androgen receptors and the consequences | veditors = Wirth M, Altwein JE, Schmitz-Dräger B, Kuptz S |title= Molecular Biology of Prostate Cancer| chapter-url = https://books.google.com/books?id=XVkiAAAAQBAJ&pg=PA92|date=1998|publisher=Walter de Gruyter|isbn=978-3-11-080727-1|pages=92–))</ref></noinclude><includeonly>See template.</includeonly>
|}<!--

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== References ==
((Reflist))
[[Category:Bicalutamide]]
[[Category:Medication templates]]
[[Category:Templates that generate named references]]
</noinclude>

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