Proteína de reparación por escisión del grupo de complementación cruzada 1 también conocida como ERCC1
Estructuras disponibles
PDB	Buscar ortólogos: PDBe, RCSB  Lista de códigos PDB 1Z00 , 2A1I , 2A1J , 2JNW , 2JPD
Identificadores
Símbolo	ERCC1 (HGNC: 3433)
Identificadores externos	OMIM: 126380 MGI: 95412 HomoloGene: 1501 EBI: ERCC1 GeneCards: Gen ERCC1 UniProt: ERCC1
Locus	Cr. 19 q13.32
Ontología génica Referencias: AmiGO / QuickGO
Patrón de expresión de ARNm
Más información
Ortólogos
Especies	Humano Ratón
Entrez	2067 13870
Ensembl	Véase HS Véase MM
UniProt	P07992 P07903
RefSeq (ARNm)	NM_001166049 NM_001127324
RefSeq (proteína) NCBI	NP_001159521 NP_001120796
Ubicación (UCSC)	Cr. 19: 45.91 – 45.98 Mb Cr. 7: 19.34 – 19.36 Mb
PubMed (Búsqueda)	[1] [2]
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La proteína de reparación por escisión del grupo de complementación cruzada 1 también conocida como ERCC1

Bibliografía

• Olaussen KA, Mountzios G, Soria JC (2007). «ERCC1 as a risk stratifier in platinum-based chemotherapy for nonsmall-cell lung cancer.». Current opinion in pulmonary medicine 13 (4): 284-9. PMID 17534174. doi:10.1097/MCP.0b013e32816b5c63. 
• van Duin M, de Wit J, Odijk H, et al. (1986). «Molecular characterization of the human excision repair gene ERCC-1: cDNA cloning and amino acid homology with the yeast DNA repair gene RAD10.». Cell 44 (6): 913-23. PMID 2420469. 
• van Duin M, van Den Tol J, Hoeijmakers JH, et al. (1989). «Conserved pattern of antisense overlapping transcription in the homologous human ERCC-1 and yeast RAD10 DNA repair gene regions.». Mol. Cell. Biol. 9 (4): 1794-8. PMID 2471070. 
• Hoeijmakers JH (1987). «Characterization of genes and proteins involved in excision repair of human cells.». J. Cell Sci. Suppl. 6: 111-25. PMID 2821019. 
• Hoeijmakers JH, van Duin M, Westerveld A, et al. (1987). «Identification of DNA repair genes in the human genome.». Cold Spring Harb. Symp. Quant. Biol. 51 Pt 1: 91-101. PMID 3034490. 
• van Duin M, van den Tol J, Warmerdam P, et al. (1988). «Evolution and mutagenesis of the mammalian excision repair gene ERCC-1.». Nucleic Acids Res. 16 (12): 5305-22. PMID 3290851. 
• Westerveld A, Hoeijmakers JH, van Duin M, et al. (1984). «Molecular cloning of a human DNA repair gene.». Nature 310 (5976): 425-9. PMID 6462228. 
• Nagai A, Saijo M, Kuraoka I, et al. (1995). «Enhancement of damage-specific DNA binding of XPA by interaction with the ERCC1 DNA repair protein.». Biochem. Biophys. Res. Commun. 211 (3): 960-6. PMID 7598728. 
• Li L, Elledge SJ, Peterson CA, et al. (1994). «Specific association between the human DNA repair proteins XPA and ERCC1.». Proc. Natl. Acad. Sci. U.S.A. 91 (11): 5012-6. PMID 8197174. 
• Park CH, Sancar A (1994). «Formation of a ternary complex by human XPA, ERCC1, and ERCC4(XPF) excision repair proteins.». Proc. Natl. Acad. Sci. U.S.A. 91 (11): 5017-21. PMID 8197175. 
• McWhir J, Selfridge J, Harrison DJ, et al. (1994). «Mice with DNA repair gene (ERCC-1) deficiency have elevated levels of p53, liver nuclear abnormalities and die before weaning.». Nat. Genet. 5 (3): 217-24. PMID 8275084. doi:10.1038/ng1193-217. 
• Trask B, Fertitta A, Christensen M, et al. (1993). «Fluorescence in situ hybridization mapping of human chromosome 19: cytogenetic band location of 540 cosmids and 70 genes or DNA markers.». Genomics 15 (1): 133-45. PMID 8432525. 
• Yu JJ, Mu C, Lee KB, et al. (1997). «A nucleotide polymorphism in ERCC1 in human ovarian cancer cell lines and tumor tissues.». Mutat. Res. 382 (1-2): 13-20. PMID 9360634. 
• Hayashi T, Takao M, Tanaka K, Yasui A (1998). «ERCC1 mutations in UV-sensitive Chinese hamster ovary (CHO) cell lines.». Mutat. Res. 407 (3): 269-76. PMID 9653453. 
• de Laat WL, Sijbers AM, Odijk H, et al. (1998). «Mapping of interaction domains between human repair proteins ERCC1 and XPF.». Nucleic Acids Res. 26 (18): 4146-52. PMID 9722633. 
• Lin YW, Kubota M, Koishi S, et al. (1998). «Analysis of mutations at the DNA repair genes in acute childhood leukaemia.». Br. J. Haematol. 103 (2): 462-6. PMID 9827920. 
• Houtsmuller AB, Rademakers S, Nigg AL, et al. (1999). «Action of DNA repair endonuclease ERCC1/XPF in living cells.». Science 284 (5416): 958-61. PMID 10320375. 
• Cheng L, Guan Y, Li L, et al. (1999). «Expression in normal human tissues of five nucleotide excision repair genes measured simultaneously by multiplex reverse transcription-polymerase chain reaction.». Cancer Epidemiol. Biomarkers Prev. 8 (9): 801-7. PMID 10498399. 
• Yu JJ, Thornton K, Guo Y, et al. (2002). «An ERCC1 splicing variant involving the 5'-UTR of the mRNA may have a transcriptional modulatory function.». Oncogene 20 (52): 7694-8. PMID 11753647. doi:10.1038/sj.onc.1204977. 
• Li QQ, Yunmbam MK, Zhong X, et al. (2002). «Lactacystin enhances cisplatin sensitivity in resistant human ovarian cancer cell lines via inhibition of DNA repair and ERCC-1 expression.». Cell. Mol. Biol. (Noisy-le-grand). 47 Online Pub: OL61-72. PMID 11936875.