In Greek mythology, Praxidice (Ancient Greek: Πραξιδίκη, [praksidíkɛː]) may refer to the following characters:

• Praxidice, goddess of judicial punishment and the exactor of vengeance, which were two closely allied concepts in the classical Greek world-view.
• Praxidice, according to the Orphic hymn to Persephone, an epithet of Persephone: "Praxidike, subterranean queen. The Eumenides' source [mother], fair-haired, whose frame proceeds from Zeus' ineffable and secret seeds."^[1] As praxis "practice, application" of dike "justice", she is sometimes identified with Dike, goddess of justice.
• Praxidice, according to Stephanus of Byzantium, a daughter of Ogygus named Praxidike, married to Tremiles (after whom Lycia had been previously named Tremile) and had by him four sons: Tlos, Xanthus, Pinarus and Cragus.^[2] Of them, Tlos had a Lycian city named Tlos after himself.^[3] Cragus may be identical with the figure of the same name mentioned as the husband of Milye, sister of Solymus.^[4]

The plural Praxidicae (Praxidikai) refers to the following groups of mythological figures who presided over exacting of justice:

• Arete and Homonoia, daughters of Praxidice and Soter, sisters to Ktesios.^[5]
• Alalcomenia, Thelxionoea and Aulis, daughters of the early Boeotian king Ogyges.^[5] At Haliartos in Boeotia, Pausanias saw the open-air "sanctuary of the goddesses whom they call Praxidikae. Here the Haliartians swear, but the oath is not one they take lightly".^[6] Their images only portrayed their heads, and only heads of animals were sacrificed to them.^[7]