The year 1529 in science and technology included a number of events, some of which are listed here.

Astronomy

• Petrus Apianus publishes Introductio Cosmographiae, cum quibusdam Geometriae ac Astronomiae principiis eam necessariis ad rem in Ingolstadt.

Chemistry

• Fluorine is first described by Georgius Agricola.^[1]
• The alchemical text Kunst- und recht Alchämei-Büchlein is published in Worms.^[2]

Technology

• Michelangelo is appointed to reconstruct the fortifications of Florence.^[2][3]

Births

• April 3 – Michael Neander, German mathematician (died 1581)
• April 25 – Franciscus Patricius (born Franjo Petriš), Venetian philosopher and scientist of Croatian descent (died 1597)
• December 16 – Laurent Joubert, French physician (died 1582)
• 1529 or 1530 – Julius Caesar Aranzi, Bolognese anatomist (died 1589)

Deaths

• Hans von Gersdorff, German surgeon (born c.1455)