The 1935 All-Big Six Conference football team consists of American football players chosen by various organizations for All-Big Six Conference teams for the 1935 college football season. The selectors for the 1935 season included the Associated Press (AP).

All-Big Six selections

Backs

• Lloyd Cardwell, Nebraska (AP-1)
• Jerry LaNoue, Nebraska (AP-1)
• Sam Francis, Nebraska (AP-1)
• Leo Ayers, Kansas State (AP-1)

Ends

• Rutherford Hayes, Kansas (AP-1)
• Bernie Scherer, Nebraska (AP-1)

Tackles

• Fred Shirey, Nebraska (AP-1)
• J. W. "Dub" Wheeler, Oklahoma (AP-1)

Guards

• Dick Sklar, Kansas (AP-1)
• Ike Hayes, Iowa State (AP-1)

Centers

• Edwin Phelps, Kansas (AP-1)

Key

AP = Associated Press^[1]