| adenosylcobinamide-phosphate guanylyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 adenosylcobinamide phosphate guanylyltransferase (CobU) from salmonella typhimurium | |||||||||
| Identifiers | |||||||||
| EC no. | 2.7.7.62 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, an adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) is an enzyme that catalyzes the chemical reaction
- GTP + adenosylcobinamide phosphate diphosphate + adenosylcobinamide-GDP
The two substrates of this enzyme are GTP and adenosylcobinamide phosphate; its two products are diphosphate and adenosylcobinamide-GDP.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is GTP:adenosylcobinamide-phosphate guanylyltransferase. Other names in common use include CobU, adenosylcobinamide kinase/adenosylcobinamide-phosphate, guanylyltransferase, and AdoCbi kinase/AdoCbi-phosphate guanylyltransferase. This enzyme is part of the biosynthetic pathway to cobalamin (vitamin B12) in bacteria.
