Johns is a surname shared by the following notable people:

• Adrian Johns (born 1951), Royal Navy vice-admiral, former Second Sea Lord and former Governor of Gibraltar
• Alan Johns (1917–1997), New Zealand scientist, chief executive and university administrator
• Alfred Johns (1868–1934), Australian cricketer, son of Peter Johns
• Andrew Johns (born 1974), Australian former rugby league footballer, brother of Matthew Johns
• Andrew Johns (triathlete) (born 1973), British triathlete
• Andy Johns (1950–2013), British music engineer
• Ben Johns (born 1999), an American professional pickleball player
• Bobby Johns (1932–2016), American former racecar driver
• Brian Johns (born 1982), Canadian Olympic swimmer
• Brian Johns (businessman) (1936–2016), Australian company director and journalist
• Catherine Johns (born 1935), museum curator and Roman archaeologist
• Charles A. Johns (1857–1932), American lawyer, jurist and politician; justice on the Supreme Court of the Philippines
• Charles Alexander Johns (1811–1874), British botanist and author
• Charley Eugene Johns (1905–1990), American politician, 32nd governor of Florida
• Chris Johns (disambiguation), several people
• Claude Hermann Walter Johns (1857–1920), English Assyriologist and Church of England clergyman
• Daniel Johns (born 1979), Australian musician
• David Johns (born 1948), American Navaho painter
• Don Johns (born 1937), Canadian retired National Hockey League player
• Doug Johns (born 1967), American retired Major League Baseball pitcher
• Emmett Johns, Canadian humanitarian
• Ethan Johns (born 1969), British music producer
• Fred Johns (1868–1932), Australian writer
• Gary Johns (born 1952), Australian politician
• Gene Johns (1927–1984), American businessman and politician
• Geoff Johns (born 1973), American comic book author
• George Sibley Johns (1857–1941), American journalist and newspaper editor
• Glyn Johns (born 1942), British record producer
• Glynis Johns (1923–2024), British actress
• Harold E. Johns (1915–1998), Canadian medical physicist
• Helen Johns (born 1953), Canadian former politician
• Helen Johns (swimmer) (1914–2014), American swimmer, Olympic champion and former world record-holder
• Henry Johns, multiple people
• James Edward Johns (1900–1984), American football player
• Jasper Johns (born 1930), American painter and printmaker
• John Johns (1796–1876), fourth Episcopal bishop of Virginia, son of Kensey Johns
• Johnny Johns (born 1951), American retired figure skater and ice dancer
• Joseph Johns (1826–1900), English convict and Australian bushranger, better known as Moondyne Joe
• Joseph Johns, Amish man who founded Johnstown, Pennsylvania in 1800
• Keith Johns (1902–1979), Australian rules footballer
• Kensey Johns (judge) (1759–1848), American judge
• Kensey Johns Jr. (1791–1857), American politician and lawyer, son of the above
• Laura M. Johns (1849–1935), American suffragist, journalist
• Les Johns (born 1942), Australian rugby league footballer
• Margo Johns (1919–2009), British actress
• Matthew Johns (born 1971), Australian Rugby League footballer of the 1990s and 2000s and channel 9 host, brother of Andrew Johns
• Mervyn Johns (1899–1992), Welsh actor, father of Glynis Johns
• Michael Johns (policy analyst) (born 1964), American political commentator, analyst and writer; former White House speechwriter
• Milton Johns (born 1938), British television actor
• Orrick Glenday Johns (1887–1946), American poet, son of George Sibley Johns
• Paddy Johns (born 1968), Irish former rugby union player
• Paul Johns (born 1958), American retired National Football League player
• Peter Johns (1830–1899), Welsh-born Australian engineer, founder of Johns & Waygood, father of Alfred Johns
• Richard Johns (born 1939), British Royal Air Force air chief marshal
• Robert J. Johns, Canadian socialist labour organizer in the 1910s
• Ronnie Johns (politician) (born 1949), American politician from Louisiana
• Sammy Johns (1946–2013), American country musician
• Sarah Johns (born 1979), American country music singer
• Stephen Johns (disambiguation)
• Stratford Johns (1925–2002), British stage, film and television actor
• Thomas Johns (minister) (1836–1914), Welsh minister
• Tony Johns (born 1960), Canadian football player
• Tracy Camilla Johns (born 1963), American film actress
• Vere Johns (1893–1966), Jamaican journalist, impresario, radio personality and actor
• Vernon Johns (1892–1965), American minister and civil rights leader
• W. E. Johns (1893–1968), British writer
• Wilbur Johns (1903–1967), American collegiate basketball head coach and athletics director