Pamela J. Russell AM FAHMS was an Australian academic researcher of immunology, bladder and prostate research.[1] Russell was awarded Membership of the Order of Australia (AM) for her research on prostate and bladder cancer in 2003.[2]

Biography

Russell was Emeritus Professor at the Institute of Health and Biomedical Innovation, Queensland University of Technology, based at the Translational Research Institute (Australia)[3] and adjunct professor, Centre for Advanced Imaging, University of Queensland.[4]

Education and training

Russell trained in immunology at Walter & Eliza Hall Institute, where she obtained an MSc with Sir Macfarlane Burnet. Subsequently, Prof. Russell completed a PhD with Sir Gustav Nossal, on studies of autoimmune diseases.[citation needed]

Russell's postdoctoral training was at the John Curtin School of Medical Research, Canberra, and then she moved to Sydney to take up a postdoctoral position at The Kolling Institute of Medical Research.[citation needed]

Russell joined the APCRC – Q in 2009.[5]

Research

Russell's early work in Immunology on Systemic Lupus Erythematosus (SLE) showed that the immunosuppressive drug, cyclophosphamide, could be successfully used to treat animals with this disease, leading to its use in patients with SLE. Early work WEHI showed that T cells could kill cancer cells.[6] Further studies of autoimmunity were performed by Russell's group at the Kolling Institute specifically SLE.[7] but also some related work in rheumatoid arthritis and in ankylosing spondylitis and its association with HLA-B27.[8][9]

Russell's focus of the work at the Kolling Institute was on autoimmunity, specifically Systemic Lupus Erythematosus (SLE),[10] but also some related work in rheumatoid arthritis and in ankylosing spondylitis and its association with HLAB27.[11][12]

In 1984, Prof. Russell changed her research focus to cancer and, with Dr. Derek Raghavan, established the Urological Cancer Research Centre at Royal Prince Alfred Hospital/University of Sydney. Prof. Russell then directed the Oncology Research Centre (ORC), Prince of Wales Hospital from 1992 to 2010, as conjoint Professor of Medicine, University of New South Wales (UNSW).

Russell then moved to the Translational Research Institute and the Australian Prostate Cancer Research Centre in Queensland in 2012.[13][14]

Awards

References

  1. ^ "Pamela Russell". www.qut.edu.au. Retrieved 12 February 2019.
  2. ^ "2003 Australia Day Honours List: AC, AO, AM". www.theage.com.au. 26 January 2003. Retrieved 12 February 2019.
  3. ^ "Pamela Russell". www.tri.edu.au. Retrieved 12 February 2019.
  4. ^ a b "Pamela Russell — Australian Prostate Cancer Research Centre - Queensland". www.australianprostatecentre.org. Archived from the original on 1 August 2017. Retrieved 6 March 2018.
  5. ^ "Professor Pamela Russell — Prostate Cancer Collaborative Research Alliance". www.aus-canprostatealliance.org.
  6. ^ Cameron, Fiona H.; Russell, Pamela J.; Easter, Joan F.; Wakefield, Denis; March, Lyn (1987). "Failure Of klebsiella pneumoniae antibodies to cross‐react with peripheral blood mononuclear cells from patients with ankylosing spondylitis". Arthritis & Rheumatism. 30 (3): 300–305. doi:10.1002/art.1780300309. PMID 3551965.
  7. ^ Cameron, F.; Russell, P.; Sullivan, J.; Geczy, A. (1983). "Is a Klebsiella plasmid involved in the aetiology of ankylosing spondylitis in HLA-b27-positive individuals?". Molecular Immunology. 20 (5): 563–566. doi:10.1016/0161-5890(83)90095-0. PMID 6348514.
  8. ^ "Cell Surface Prostate Cancer Antigen for Diagnosis". Retrieved 22 May 2019.
  9. ^ "Minomic secures key patent in the United States and China". 5 September 2018. Retrieved 22 May 2019.
  10. ^ Russell, Pamela J., and Alfred D. Steinberg. "Studies of peritoneal macrophage function in mice with systemic lupus erythematosus: Depressed phagocytosis of opsonized sheep erythrocytes in vitro." Clinical immunology and immunopathology 27, no. 3 (1983): 387-402.
  11. ^ Cameron, Fiona H., Pamela J. Russell, Joan F. Easter, Denis Wakefield, and Lyn March. "Failure Of klebsiella pneumoniae antibodies to cross‐react with peripheral blood mononuclear cells from patients with ankylosing spondylitis." Arthritis & Rheumatism 30, no. 3 (1987): 300-305.
  12. ^ Cameron, Fiona H., Pamela J. Russell, John Sullivan, and Andrew F. Geczy. "Is a Klebsiella plasmid involved in the aetiology of ankylosing spondylitis in HLA-B27-positive individuals?." Molecular Immunology 20, no. 5 (1983): 563-566.
  13. ^ "Vale Emeritus Professor Pamela Russell AM FAHMS". Australian Academy of Health and Medical Sciences. 10 March 2022. Retrieved 12 March 2022.
  14. ^ a b "Remembering The Late Professor Pamela Russell AM". Funding Cancer Research | Cure Cancer. 2 March 2022. Retrieved 12 March 2022.
  15. ^ "APCRC - Q Researcher Wins PCFA Award". Retrieved 12 February 2019.
  16. ^ "Fellowship of the Australian Academy of Health and Medical Sciences October 2015" (PDF). Retrieved 12 February 2019.
  17. ^ "Pam Russell AM Alumni Excellence Award Health Winner". Retrieved 12 February 2019.