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((Navbox
| name       = Deficiencies of intracellular signaling peptides and proteins
| title      = Deficiencies of intracellular signaling peptides and proteins
| state      = (({state|autocollapse))}
| listclass  = hlist

| group1 = [[GTP-binding protein regulators]]
| list1  =
  ((Navbox|subgroup
  | group1 = [[GTPase-activating protein]]
  | list1  = 
* [[Neurofibromatosis type I]]
* [[Watson syndrome]]
* [[Tuberous sclerosis]]

  | group2 = [[Guanine nucleotide exchange factor|Guanine nucleotide<br/>exchange factor]]
  | list2  = 
* [[Marinesco–Sjögren syndrome]]
* [[Aarskog–Scott syndrome]]
* [[Juvenile primary lateral sclerosis]]
* [[X-linked intellectual disability|X-linked intellectual disability 1]]
  ))

| group4 = [[G protein]]
| list4  =
  ((Navbox|subgroup
  | group1 = [[Heterotrimeric G protein|Heterotrimeic]]
  | list1  = 
* [[cAMP-dependent pathway|cAMP]]/[[GNAS complex locus|GNAS1]]: [[Pseudopseudohypoparathyroidism]]
* [[Progressive osseous heteroplasia]]
* [[Pseudohypoparathyroidism]]
* [[Albright's hereditary osteodystrophy]]
* [[McCune–Albright syndrome]]
* [[Congenital generalized lipodystrophy|CGL 2]]

  | group2 = [[Small GTPase|Monomeric]]
  | list2  = 
* RAS: ''[[HRAS]]''
** [[Costello syndrome]]
* ''[[KRAS]]''
** [[Noonan syndrome|Noonan syndrome 3]]
** [[Cardiofaciocutaneous syndrome|KRAS Cardiofaciocutaneous syndrome]]

* RAB: ''[[RAB7A|RAB7]]''
** [[Charcot–Marie–Tooth disease]]
* ''[[RAB23]]''
** [[Carpenter syndrome]]
* ''[[RAB27]]''
** [[Griscelli syndrome type 2]]

* RHO: ''[[RAC2]]''
** [[Neutrophil immunodeficiency syndrome]]

* [[ADP ribosylation factor|ARF]]: ''[[SAR1B]]''
** [[Chylomicron retention disease]]
* ''[[ARL13B]]''
** [[Joubert syndrome|Joubert syndrome 8]]
* ''[[ARL6]]''
** [[Bardet–Biedl syndrome|Bardet–Biedl syndrome 3]]
  ))

| group5 = [[Mitogen-activated protein kinase|MAP kinase]]
| list5  = 
* [[Cardiofaciocutaneous syndrome]]

| group6 = Other [[kinase]]/[[phosphatase]]
| list6  =
  ((Navbox|subgroup
  | group1 = [[Non-receptor tyrosine kinase|Tyrosine kinase]]
  | list1  = 
* ''[[Bruton's tyrosine kinase|BTK]]''
** [[X-linked agammaglobulinemia]]
* ''[[ZAP70]]''
** [[ZAP70 deficiency]]

  | group2 = [[Serine/threonine-specific protein kinase|Serine/threonine<br/>kinase]]
  | list2  = 
* ''[[RPS6KA3]]''
** [[Coffin–Lowry syndrome|Coffin-Lowry syndrome]]
* ''[[CHEK2]]''
** [[Li–Fraumeni syndrome|Li–Fraumeni syndrome 2]]
* ''[[IKBKG]]''
** [[Incontinentia pigmenti]]
* ''[[STK11]]''
** [[Peutz–Jeghers syndrome]]
* [[Myotonin-protein kinase|DMPK]]
** [[Myotonic dystrophy|Myotonic dystrophy 1]]
* ''[[Ataxia telangiectasia and Rad3 related|ATR]]''
** [[Seckel syndrome|Seckel syndrome 1]]
* ''[[Rhodopsin kinase|GRK1]]''
** [[Oguchi disease|Oguchi disease 2]]
* ''[[WNK4]]''/''[[WNK1]]''
** [[Pseudohypoaldosteronism|Pseudohypoaldosteronism 2]]

  | group3 = [[Protein tyrosine phosphatase|Tyrosine<br/> phosphatase]]
  | list3  = 
* ''[[PTEN (gene)|PTEN]]''
** [[Bannayan–Riley–Ruvalcaba syndrome]]
** [[Lhermitte–Duclos disease]]
** [[Cowden syndrome]]
** [[Proteus-like syndrome]]
* ''[[Myotubularin 1|MTM1]]''
** [[X-linked myotubular myopathy]]
* ''[[PTPN11]]''
** [[Noonan syndrome|Noonan syndrome 1]]
** [[LEOPARD syndrome]]
** [[Metachondromatosis]]
  ))

| group7 = [[Signal transducing adaptor protein]]s
| list7  = 
* ''[[EDARADD]]''
** [[Hypohidrotic ectodermal dysplasia|EDARADD Hypohidrotic ectodermal dysplasia]]
* ''[[SH3BP2]]''
** [[Cherubism]]
* ''[[LDB3]]''
** [[Zaspopathy]]

| group8 = Other
| list8  = 
* ''[[Merlin (protein)|NF2]]''
** [[Neurofibromatosis type II]]
* ''[[Notch 3]]''
** [[CADASIL]]
* ''[[PRKAR1A]]''
** [[Carney complex]]
* ''[[PRKAG2]]''
** [[Wolff–Parkinson–White syndrome]]
* ''[[PRKCSH]]''
** [[Polycystic liver disease|PRKCSH Polycystic liver disease]]
* ''[[XIAP]]''
** [[X-linked lymphoproliferative disease|XIAP2]]

| below = ''See also [[Template:Intracellular signaling peptides and proteins|intracellular signaling peptides and proteins]]'' 
))<noinclude>
((collapsible option))
[[Category:Deficiencies of intracellular signaling peptides and proteins]]
[[Category:Genetic disease and disorder templates by mechanism]]
</noinclude>

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