Two ships of the United States Navy have been named USS Chase.

• USS Chase (DD-323), a Clemson-class destroyer, commissioned in 1921 and decommissioned in 1930. It was named after Reuben Chase.
• USS Chase (DE-158), a Buckley-class destroyer escort, commissioned in 1943 and decommissioned in 1946. It was named for Admiral Jehu V. Chase.

Other ships

• USS Edgar G. Chase, a WWII Evarts-class destroyer escort
• USS Samuel Chase, a WWII Arthur Middleton-class attack transport, named for signer of the Declaration of Independence Samuel Chase