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APETx1 article - Infobox error[edit]

Greetings, For article APETx1, at top it shows error line in red, Unknown parameter SequenceUnknown parameter Amino Acid Sequence. Asking for help here as I know almost nothing of the topic. Regards, JoeNMLC (talk) 20:01, 15 February 2024 (UTC)[reply]

The infobox parameters have been corrected, thank you. ― Synpath 20:40, 18 February 2024 (UTC)[reply]

Delete "Gene expression" article[edit]

I propose that we delete the article on Gene expression and replace it with redirects to relevant material found elsewhere such as Transcription, Translation, and Regulation of gene expression.

It's a bad idea to have multiple articles covering the same topic, especially when they conflict. Also, the Gene expression article is far too big and full of extraneous technical information that's way beyond the level we should be aiming at.Genome42 (talk) 21:47, 17 February 2024 (UTC)[reply]

Gene expression is a fundamental topic in molecular biology; we need an article on the topic. I agree there are many facets to this broad and deep topic. The current organization, which introduces the topic, provides summaries and links to other more specialized topics, seems a good structure to reflect these facets. If there are sections that are too technical, those would be good candidates for a rewrite, but not a deletion. Let's not delete the forest to get at the trees. --((u|Mark viking)) {Talk} 00:23, 18 February 2024 (UTC)[reply]
Gene expression is represented as a whole process in biology textbooks. With the use of "Main article" templates, more interested reader shoudn't face any problems with finding more information. InternetowyGołąb (talk) 03:06, 18 February 2024 (UTC)[reply]
As a textbook writer and teacher I'm quite familiar with how the topic of gene expression is covered in molecular biology. We usually cover transcription and translation in some detail then we cover the basics of regulation of gene expression. All three of those topics are presented in separate articles on Wikipedia.
There's nothing in the article on gene expression that's not found elsewhere. The problem isn't just redundancy. It's that various editors insert their own biases and (possibly) misinformation into the various articles so that the more articles we have the greater the chance that they will conflict. There aren't very many of us working on these articles so let's concentrate on getting a few articles correct. Genome42 (talk) 21:09, 18 February 2024 (UTC)[reply]
Check out the Gene expression article to see examples extraneous information. There are sections on "Folding," "Translocation," and "Protein transport." Are those really relevant topics in an article on gene expression?
The section on "Regulation of gene expression" only talks about the complex mechanisms in eukaryotes. There's nothing about the lac operon or the other fundamental examples in bacteria. There's nothing about how a transcription factor finds the right gene. Some of the material that's in that section is either incomplete or misleading. There's a section on methylation that doesn't even mention chromatin and doesn't explain why some CpGs are demethylated.
There's an entire section on "Transcriptional regulation in learning and memory" and another on "Transcriptional regulation in cancer." Really? There's a lengthy section on "Measurement" that's far too detailed, boring, and doesn't cite any sources. Does anybody really want to waste time cleaning up this article?Genome42 (talk) 21:34, 18 February 2024 (UTC)[reply]
Gene expression is a solid example of a WP:BROAD concept. I don't think you could redirect the term to a single article and have that be satisfactory. I don't think it would be possible to build it into a disambiguation either. The current organization of a set of summarized subtopics linking to main articles is likely the best way of handling the term. Though I do agree that the article has bloat. ― Synpath 21:36, 18 February 2024 (UTC)[reply]

"Random sequencing"[edit]

On our Mycoplasma genitalium article, it says:

They performed an initial study of the genome using random sequencing in 1993

where "random sequencing" links to Random sequence (the mathematical concept). What should it link to instead? Marnanel (talk) 13:39, 2 March 2024 (UTC)[reply]

It should link to DNA sequencing where you can find descriptions of early sequencing techniques. Randomness is a core part of several techniques, but there's no dedicated section describing its use in that article. I don't think that the word 'random' should be part of the wikilink. ― Synpath 16:17, 2 March 2024 (UTC)[reply]
Done— thank you. I note that "random" was in the title and abstract of the linked paper, which is presumably where the previous editor found it. Marnanel (talk) 21:04, 2 March 2024 (UTC)[reply]

Zoonotic origins of COVID-19[edit]

Zoonotic origins of COVID-19 has been nominated at Articles for Deletion. Interested editors may participate at Wikipedia:Articles for deletion/Zoonotic origins of COVID-19. TarnishedPathtalk 09:47, 9 March 2024 (UTC)[reply]

Unused PDB Gallery templates[edit]

Hey everyone, the following PDB Gallery templates are not used anywhere. If you know where they should be used, please use them in the relevant articles. If they aren't needed please let me know.

Thanks! Gonnym (talk) 15:39, 13 March 2024 (UTC)[reply]

Appropriate template for gene/protein synonyms[edit]

Recently I made some protein or gene (article about protein with title being gene descriptor) synonymous names redirects, and I wonder what would be the appropriate "R from..." tracking category template. InternetowyGołąb (talk) 13:15, 23 March 2024 (UTC)[reply]

@InternetowyGołąb We have alternatives like ((R from acronym)) and ((R from initialism)) as well as the tracking Category ((R from alternative name)) I see you have used for NAXE. The template pages give guidance on which to use: in some cases more than one is appropriate. Mike Turnbull (talk) 12:08, 8 April 2024 (UTC)[reply]

Atavism: Real or psuedoscience?[edit]

Folks - quick question because I'm not a biologist or scientist by any stretch of the imagination. Is Atavism real or is this a psuedoscience article that has evaded detection? There appears to be a lot of synthesis or original research.-- (talk) 03:12, 8 April 2024 (UTC)[reply]

Atavism seems to be a legitimate concept but it wouldn't surprise me if it's sometimes used by fringe claims. Jo-Jo Eumerus (talk) 07:07, 8 April 2024 (UTC)[reply]
Since it is tagged with ((Original research)), it does look like the article needs to be bolstered with citations. Peaceray (talk) 07:40, 8 April 2024 (UTC)[reply]
Possibly a bit of both. A Google Scholar search for "atavism" in article titles gives over 100 hits since the year 2010, of which this article is a reasonable review. Mike Turnbull (talk) 11:50, 8 April 2024 (UTC)[reply]

Requested move at Talk:3α-Hydroxysteroid dehydrogenase#Requested_move_9_April_2024[edit]

There is a requested move discussion at Talk:3α-Hydroxysteroid dehydrogenase#Requested_move_9_April_2024 that may be of interest to members of this WikiProject. Natg 19 (talk) 23:23, 18 April 2024 (UTC)[reply]

MID gene[edit]

Just a quick question is there any articles about a gene in particular? I’m talking about a gene called MID (minus dominance). There does seem to be a lot of sources about this gene from:




Just asking to make sure it doesn’t go by a different name or something. I’m also wondering if genes here on Wikipedia have a certain style or policies.

Also I am bringing this up to see what y’all think about there being an article on this gene. When researching the evolution of sexes and mating types I noticed a lot of sources keep mentioning this gene.CycoMa1 (talk) 04:52, 2 May 2024 (UTC)[reply]

Wikipedia is a popular encyclopedia intended for a diverse audience. There are 25,000 genes in the human genome and something close to one million different different genes in the biosphere. We do not need to have a separate Wikipedia article for each gene.
But there's another problem that just as important. Any article on an individual genes is certainly going to bring up the definition of a gene and important issues such as regulation, evolution, and alternative splicing. It is proving to be very difficult to get individual editors to stick to the definitions and descriptions of these features that have been thrashed out in the articles specific to those topics. This leads to a lot of confusion and conflict so we should be very cautious about creating any new molecular biology articles unless they are absolutely necessary. Genome42 (talk) 14:57, 2 May 2024 (UTC)[reply]