Protein-coding gene in the species Homo sapiens
Chloride intracellular channel protein 6 is a protein that in humans is encoded by the CLIC6 gene.[5][6]
The CLIC6 gene encodes a member of the chloride intracellular channel family of proteins. The gene is part of a large triplicated region found on chromosomes 1, 6, and 21. An alternatively spliced transcript variant has been described, but its biological validity has not been determined.[6]
Interactions
CLIC6 has been shown to interact with Dopamine receptor D3.[7]
Function
CLIC6 has been shown to form chloride selective redox and pH regulated ion channels. It is predominantly expressed in the plasma membrane of lung epithelial cells. [8]