This list compares the features and functionality of application servers, grouped by the hosting environment that is offered by that particular application server.

C

• Enduro/X – A middleware platform for distributed transaction processing, based on XATMI and XA standards, open source, C API

C++

• Tuxedo – Based on the ATMI standard, is one of the original application servers.
• Wt – A web toolkit similar to Qt permitting GUI-application-like web development with built-in Ajax abilities.
• POCO C++ Libraries – A set of open source class libraries including Poco.Net.HTTPServer.html
• CppCMS
• Enduro/X – A middleware platform for distributed transaction processing, based on XATMI and XA standards, open source

Go

• Enduro/X ASG – Application server for Go. This provides XATMI and XA facilities for Golang. Go application can be built by normal Go executable files which in turn provides stateless services, which can be load balanced, clustered and reloaded on the fly without service interruption by means of administrative work only. Framework provides distributed transaction processing facility for Go.

Java

• Apache MINA – an abstract event-driven asynchronous API over various transports such as TCP/IP and UDP/IP via Java NIO
• Netty – a non-blocking I/O client-server framework for the development of Java network applications similar in spirit to Node.js

JavaScript

• Broadvision – Server-side JavaScript AS. One of the early entrants in the market during the eCommerce dot-com bubble, they have vertical solution packages catering to the eCommerce industry.
• Node.js – implements Google's V8 engine as a standalone (outside the browser) asynchronous Javascript interpreter. A vigorous open-source developer community on GitHub has implemented many supporting products, notably npm for package management and Connect and Express app server layers.
• Deno – community developed Rust project, spearheaded by Ryan Dahl who also created Node.js, it directly targets TypeScript but also supports JavaScript and WebAssembly via V8; employs asynchronous, event-based I/O model via promise-based APIs and Tokio scheduler, uses an API security model via FlatBuffers and implements package management via ES2015 modules.
• Phusion Passenger

LPC

• Dworkin's Game Driver (DGD)

Lua

• OpenResty
• Tarantool

.NET

Microsoft

Microsoft positions their middle-tier applications and services infrastructure in the Windows Server operating system and the .NET Framework technologies in the role of an application server:

• Internet Information Services web server
• .NET Framework (Windows Communication Foundation, Web Services, .NET Remoting, Microsoft Message Queuing (MSMQ), ASP.NET, ADO.NET)
• Distributed Transactions, COM+
• Active Directory Lightweight Directory Service (ADLDS), Active Directory Federation Services (ADFS), Authorization Manager

Third-party

• Mono – Developed by Xamarin, licensed under MIT

Objective-C

• GNUstepWeb - WebObjects 4.5 compatible, licensed under LGPL

PHP

• Appserver.io, an open-source PHP application server.
• RoadRunner, built by Spiral Scout is high-performance PHP application server, load-balancer and process manager written in Golang.

Python

• uWSGI
• Gunicorn
• CherryPy
• Google App Engine
• mod_python
• mod_wsgi
• Phusion Passenger
• Paste
• Tornado
• Twisted
• Web2py
• Zope – By Zope, Inc.

Ruby

• Mongrel
• Passenger
• Puma
• Unicorn

Smalltalk

• Seaside – A continuations based web application server

Tcl

• AOLserver – Forked from NaviServer after developer was bought by AOL in 1995
• NaviServer – Resumed independent development after AOL dropped AOLserver support.