Liver abscess
Leberabszess - CT axial PV.jpg
Liver abscess on axial CT image: a hypodense lesion in the liver with peripherally enhancement.
SpecialtyGastroenterology Edit this on Wikidata

A liver abscess is a mass filled with pus inside the liver.[1] Common causes are abdominal conditions such as appendicitis or diverticulitis due to haematogenous spread through the portal vein.[2] It can also develop as a complication of a liver injury.

Causes

Risk factors for developing liver abscess can be due to infection, post-procedural infection and metastasis such as primary liver tumours, liver metastasis, biliary procedures, biliary injuries, biliary tract disease, appendicitis, and diverticulitis.[citation needed]

Major bacterial causes of liver abscess include the following:[3]

However, as noted above, many cases are polymicrobial.

Diagnosis

Types

A large pyogenic liver abscess presumed to be the result of appendicitis
A large pyogenic liver abscess presumed to be the result of appendicitis

There are several major forms of liver abscess, classified by cause:[citation needed]

Management

Antibiotics: IV metronidazole and third generation cephalosporin/quinolones, β-lactam antibiotics, and aminoglycosides are effective.[citation needed]

Prognosis

The prognosis has improved for liver abscesses. The mortality rate in-hospital is about 2.5-19%. The elderly, ICU admissions, shock, cancer, fungal infections, cirrhosis, chronic kidney disease, acute respiratory failure, severe disease, or disease of biliary origin have a worse prognosis.[4]

References

  1. ^ "Liver Abscess Definition in Medical Conditions Dictionary". medconditions.net. 11 April 2018. Retrieved 11 April 2018.
  2. ^ MedlinePlus Encyclopedia: Pyogenic liver abscess
  3. ^ Webb GJ, Chapman TP, Cadman PJ, Gorard DA (January 2014). "Pyogenic liver abscess". Frontline Gastroenterology. 5 (1): 60–67. doi:10.1136/flgastro-2013-100371. PMC 5369710. PMID 28839753.
  4. ^ Akhondi H, Sabih DE (2019). "Liver Abscess". StatPearls. StatPearls Publishing. PMID 30855818. Retrieved 2019-07-28.