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My suggestions on how to improve this article are:
Try and avoid technical terms or jargon as much as possible, if technical terms need to be used, explain or qualify what it means in parenthesis on first use. Alternatively provide an internal link to an article that describes the term. A few examples of text that will be very hard for non-experts to understand:
"GO term"
"...in situ reporter (e.g. knock-in and gene trap) data."
"EMAGE entries are designed to adhere to the MISFISHIE[4] specifications"
"It includes wholemount data, section data.."
Avoid linking externally in the main text. Provide those links as an inline references and instead link to an Wikipedia article (even if it doesn't exist yet) on first use (e.g. "...MGI Gene Expression Database (GXD)" should be "...MGI Gene Expression Database (GXD)[1]"
A short background section would be nice; for example, why and in what context was the database developed, how does it interface with related databases such as emap?
A short section on technical aspects would be nice; for example how many images, or assays or genes does it contain data for. What language is it programmed in, how many versions?
I've added an infobox that you can complete. See Rfam as an example or Template:Infobox biodatabase for the documentation. I can upload of the logo if you can send it to me, or direct me to a link to the file.