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Recent work by dos Santos et al. (http://www.ncbi.nlm.nih.gov/pubmed/24835571) brings into question the effect of Mbd3 overexpression/deletion on the induction of pluripotency in somatic cells. This work suggests that Mbd3 is important for efficient iPS production and that its deletion greatly reduces efficiency. — Preceding unsigned comment added by Lozzabates (talk • contribs) 18:12, 2 July 2014 (UTC)Reply[reply]