Structures of three kinds of amides: an organic amide (carboxamide), a sulfonamide, and a phosphoramide.

In chemistry, the term amide (/ˈæmd/ or /ˈæmɪd/ or /ˈmd/)[1][2][3] is a compound with the functional group RnE(=O)xNR2, where n and x may be 1 or 2, E is some element, and each R represents an organic group or hydrogen.[4] It is a derivative of an oxoacid RnE(=O)xOH with an hydroxy group –OH replaced by an amine group –NR2.

Some important subclasses are

The term amide may also refer to

There is also a neutral amino radical (•NH2) and a positively charged NH2+ ion called a nitrenium ion, but both of these are very unstable.

See also


  1. ^ "Amide definition and meaning - Collins English Dictionary". Retrieved 15 April 2018.
  2. ^ "amide". The American Heritage Dictionary of the English Language (5th ed.). HarperCollins.
  3. ^ "amide - Definition of amide in English by Oxford Dictionaries". Oxford Dictionaries - English. Archived from the original on April 2, 2015. Retrieved 15 April 2018.
  4. ^ IUPAC, Compendium of Chemical Terminology, 2nd ed. (the "Gold Book") (1997). Online corrected version: (2006–) "amides". doi:10.1351/goldbook.A00266