It has been suggested that Abirritant be merged into this article. (Discuss) Proposed since May 2021.

Antipruritics, also known as anti-itch drugs, are medications that inhibit the itching (Latin: pruritus) often associated with sunburns, allergic reactions, eczema, psoriasis, chickenpox, fungal infections, insect bites and stings like those from mosquitoes, fleas, and mites, and contact dermatitis and urticaria caused by plants such as poison ivy (urushiol-induced contact dermatitis) or stinging nettle.

Common antipruritics

Topical antipruritics in the form of creams and sprays are often available over the counter. The active ingredients usually belong to these classes:

Oral antipruritics also exist and are usually prescription drugs. These can be antihistamines as above[2] or:

Disputed and questionable antipruritics

Home remedies


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  2. ^ Stöppler, Melissa Conrad. "Itch (Itching or Pruritus)". MedicineNet. Retrieved 3 June 2019.
  3. ^ Inui, Shigeki (2015). "Nalfurafine hydrochloride to treat pruritus: a review". Clinical, Cosmetic and Investigational Dermatology. 8: 249–55. doi:10.2147/CCID.S55942. ISSN 1178-7015. PMC 4433050. PMID 26005355.
  4. ^ Long, D.; Ballentine, N. H.; Marks, J. G. (September 1997). "Treatment of poison ivy/oak allergic contact dermatitis with an extract of jewelweed". Am. J. Contact. Dermat. 8 (3): 150–3. doi:10.1097/01206501-199709000-00005. PMID 9249283.
  5. ^ Gibson, M. R.; Maher, F. T. (May 1950). "Activity of jewelweed and its enzymes in the treatment of Rhus dermatitis". J. Am. Pharm. Assoc. 39 (5): 294–6. doi:10.1002/jps.3030390516. PMID 15421925.
  6. ^ Guin, J. D.; Reynolds, R. (June 1980). "Jewelweed treatment of poison ivy dermatitis". Contact Dermatitis. 6 (4): 287–8. doi:10.1111/j.1600-0536.1980.tb04935.x. PMID 6447037.
  7. ^ Zink, B. J.; Otten, E.J.; Rosenthal, M.; Singal, B (1991). "The Effect Of Jewel Weed In Preventing Poison Ivy Dermatitis". Journal of Wilderness Medicine. 2 (3): 178–182. doi:10.1580/0953-9859-2.3.178. Retrieved 2008-01-16.[permanent dead link]
  8. ^ Lee CS, Koo J (2005). "Psychopharmacologic therapies in dermatology: an update". Dermatologic Clinics. 23 (4): 735–44. doi:10.1016/j.det.2005.05.015. PMID 16112451.
  9. ^ "American Topics. An Outdated Notion, That Calamine Lotion". Archived from the original on 19 June 2007. Retrieved 2007-07-19.
  10. ^ Appel, L.M. Ohmart; Sterner, R.F. (1956). "Zinc oxide: A new, pink, refractive microform crystal". AMA Arch Dermatol. 73: 316–324. PMID 13301048.
  11. ^ September 2, 2008 FDA Document Archived July 16, 2010, at the Wayback Machine
  12. ^ a b Paul Tawrell, Wilderness Camping and Hiking(Falcon Distribution, 2008), 212.