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Trade names | Brenzavvy, Bexacat |
AHFS/Drugs.com | Micromedex Detailed Consumer Information |
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Routes of administration | By mouth |
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Formula | C24H29ClO7 |
Molar mass | 464.94 g·mol−1 |
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Bexagliflozin, sold under the brand name Brenzavvy, is an antidiabetic medication used to improve glycemic control in adults with type 2 diabetes as an adjunct to diet and exercise.[4] It is a sodium-glucose cotransporter 2 (SGLT2) inhibitor that is taken by mouth.[1][2]
Bexagliflozin is indicated to improve glycemic control in adults with type 2 diabetes as an adjunct to diet and exercise.[3][4]
A 96-week phase II clinical study of adults with type 2 diabetes showed that bexagliflozin monotherapy provided a durable, clinically meaningful improvement of glycemic control, with a substantial reduction in weight and blood pressure, but no increase in the rate of significant adverse events.[5][6] In a clinical study of patients with type 2 diabetes and stage 3a/3b chronic kidney disease, bexagliflozin was well tolerated and shown to reduce hemoglobin A1c levels, body weight, systolic blood pressure and albuminuria.[7]
The data from two six-month field studies and an extended use field study demonstrated that bexagliflozin was over 80% effective in improving glycemic control in cats with diabetes mellitus.[2]
Bexagliflozin, sold under the brand name Bexacat, is an antidiabetic medication used to improve glycemic control in cats with diabetes.[2] Bexacat is the first sodium-glucose cotransporter 2 (SGLT2) inhibitor new animal drug approved by the US Food and Drug Administration (FDA) in any animal species.[2] It was approved for medical use in the United States in December 2022.[2][8] Bexacat is sponsored by Increvet Inc., based in Boston, Massachusetts.[2] Elanco licensed development and commercialization rights for bexagliflozin from Bexcafe, an affiliate of Increvet.[8]