Names | |
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IUPAC name
(2S)-4′,7-Dihydroxyflavan-4-one
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Systematic IUPAC name
(2S)-7-Hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-1-benzopyran-4-one | |
Identifiers | |
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3D model (JSmol)
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ChEBI | |
ChEMBL | |
ChemSpider | |
KEGG | |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C15H12O4 | |
Molar mass | 256.257 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Liquiritigenin is a flavanone that was isolated from Glycyrrhiza uralensis, and is found in a variety of plants of the Glycyrrhiza genus, including Glycyrrhiza glabra (licorice).[1] It is an estrogenic compound which acts as a selective agonist of the ERβ subtype of the estrogen receptor (ER),[2] though it is also reported to act as an ERα partial agonist at sufficient concentrations.[3] It also has a choleretic effect.[1]
Liquiritigenin,NADPH:oxygen oxidoreductase (hydroxylating, aryl migration) is an enzyme that uses liquiritigenin, O2, NADPH and H+ to produce 2,7,4'-trihydroxyisoflavanone, H2O, and NADP+.
Flavanones and their glycosides | |
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Flavanones | |
O-methylated flavanones |
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C-methylated flavanones | |
Glycosides |
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Acetylated | |
Acetylated glycosides |
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Phytoestrogens |
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Mycoestrogens |
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Metalloestrogens |