Biological databases are stores of biological information.[1] The journal Nucleic Acids Research regularly publishes special issues on biological databases and has a list of such databases. The 2018 issue has a list of about 180 such databases and updates to previously described databases.[2] Omics Discovery Index can be used to browse and search several biological databases.

Meta databases

Meta databases are databases of databases that collect data about data to generate new data. They are capable of merging information from different sources and making it available in a new and more convenient form, or with an emphasis on a particular disease or organism.[metadatabase is a database model for metadata management, global query of independent database, and distributed data processing. The word metadatabase is an addition to the dictionary]. originally ,metadata was only common term referring simply to data about data such a tags ,keywords, and markup headers.

Model organism databases

Model organism databases provide in-depth biological data for intensively studied organisms.

Nucleic acid databases

DNA databases

Primary databases
International Nucleotide Sequence Database (INSD) consists of the following databases.

DDBJ (Japan), GenBank (USA) and European Nucleotide Archive (Europe) are repositories for nucleotide sequence data from all organisms. All three accept nucleotide sequence submissions, and then exchange new and updated data on a daily basis to achieve optimal synchronisation between them. These three databases are primary databases, as they house original sequence data. They collaborate with Sequence Read Archive (SRA), which archives raw reads from high-throughput sequencing instruments.

Secondary databases

Other databases

Gene expression databases (mostly microarray data)

Main article: Microarray databases

Genome databases

These databases collect genome sequences, annotate and analyze them, and provide public access. Some add curation of experimental literature to improve computed annotations. These databases may hold many species genomes, or a single model organism genome.

Phenotype databases

RNA databases

Amino acid / protein databases

Protein sequence databases

Protein structure databases

For more protein structure databases, see also Protein structure database.

Protein model databases

Protein-protein and other molecular interactions

Protein expression databases

Signal transduction pathway databases

Metabolic pathway and protein function databases

Additional databases

Exosomal databases

Mathematical model databases

Taxonomic databases

Main article: List of biodiversity databases

Radiologic databases

Antimicrobial resistance databases

Wiki-style databases

Specialized databases

References

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  19. ^ CEEHRC
  20. ^ Blueprint
  21. ^ EGA
  22. ^ DEEP
  23. ^ CREST
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