This is a list of progestogen esters, or esters of progestogens.[1][2][3][4][5]
Unlike the case of testosterone and estradiol, progesterone cannot be esterified as it lacks hydroxyl groups, so all progestogen esters, with the exception of esters of 17α-hydroxyprogesterone like hydroxyprogesterone caproate, are esters of progestins (synthetic progestogens) and are non-bioidentical. In addition, whereas all androgen and estrogen esters are prodrugs of the parent compound, only some and not all progestogen esters act as prodrugs. Esters of 17α-hydroxyprogesterone and 19-norprogesterone derivatives like hydroxyprogesterone caproate, medroxyprogesterone acetate, and nomegestrol acetate are active themselves and are not prodrugs, whereas esters of 19-nortestosterone derivatives like norethisterone acetate and norethisterone enanthate are not active themselves and are prodrugs.
The following major progestogen esters have been marketed:
And the following minor progestogen esters have been marketed:
The following veterinary-only progestogen esters have also been marketed:
The corticosteroid ester mometasone furoate (Asmanex, Elocom, Elocon, Elosalic, Nasonex), which is a 17α-hydroxyprogesterone derivative, also has very potent progestogenic activity, though it is not used as a progestogen and is instead used exclusively as a corticosteroid.[6]
The following progestogen esters have been marketed:
And the following veterinary-only progestogen esters have also been marketed:
The following progestogen esters have been marketed:
Many 19-nortestosterone androgen esters, such as nandrolone esters like nandrolone decanoate (Deca-Durabolin) and nandrolone phenpropionate (Durabolin), also have potent progestogenic activity.
Although not esters, the following progestogen ethers have been marketed:
See also: List of corticosteroid cyclic ketals |
Although not esters, the following progestogen cyclic ketals (cyclic acetals) have been marketed:
Although not esters, the following progestogen oximes have not been marketed:
Although not esters, the following progestogen oximes have been marketed: