This is a list of progestogens (progesterone and progestins ) and formulations that are approved by the FDA Tooltip Food and Drug Administration in the United States. Progestogens are used as hormonal contraceptives , in hormone replacement therapy for menopausal symptoms , and in the treatment of gynecological disorders .[medical citation needed ]
For contraception
Combined contraceptives
Combined oral contraceptive pills
Drospirenone and Estetrol (Nextstellis)
Estradiol valerate and dienogest (Natazia)
Ethinylestradiol and desogestrel (Bekyree, Cyclessa, Desogen, Emoquette, Enskyce, Isibloom, Kariva, Kimidess, Mircette, Ortho-Cept, Pimtrea, Velivet, Viorele, Volnea)
Ethinylestradiol and drospirenone [and/or levomefolate calcium ] (Beyaz, Loryna, Melamisa, Nikki, Safyral, Syeda, Yaela, Yasmin, Yaz)
Ethinylestradiol and etynodiol diacetate (Demulen 1/35-21, Demulen 1/35-28, Demulen 1/50-21, Demulen 1/50-28, Kelnor, Zovia 1/35E-21, Zovia 1/35E-28, Zovia 1/50E-21, Zovia 1/50E-28)
Ethinylestradiol and levonorgestrel (Alesse, Altavera, Ashlyna, Aviane-21, Aviane-28, Ayuna, Daysee, Elifemme, Enpresse-21, Enpresse-28, Falmina, Fayosim, Introvale, Kurvelo, Lessina-21, Lessina-28, Levlite, Levonest, Levonorgestrel and Ethinyl Estradiol, Levora 0.15/30-21, Levora 0.15/30-28, LoSeasonique, Lybrel, Marlissa, Myzilra, Nordette-21, Nordette-28, Orsythia, Portia-21, Portia-28, Preven Emergency Contraceptive Kit, Quartette, Quasense, Seasonale, Seasonique, Setlakin, Triphasil-21, Triphasil-28, Trivora-21, Trivora-28, Vienva)
Ethinylestradiol and norethisterone [and/or ferrous fumarate (Fe)] (Alyacen 1/35, Alyacen 7/7/7, Alyacen 777, Aranelle, Balziva-21, Balziva-28, Brevicon 21-Day, Brevicon 28-Day, Briellyn, Cyclafem 0.5/35, Cyclafem 1/35, Cyclafem 7/7/7, Dasetta 1/35, Dasetta 7/7/7, Femcon Fe, Gencept 10/11-21, Gencept 10/11-28, Gildagia, Kaitlib Fe, Modicon 21, Modicon 28, N.E.E. 1/35 21, N.E.E. 1/35 28, Norcept-E 1/35 21, Norcept-E 1/35 28, Norethin 1/35E-21, Norethin 1/35E-28, Norinyl 1+35 21-Day, Norinyl 1+35 28-Day, Norquest Fe, Nortrel 0.5/35-21, Nortrel 0.5/35-28, Nortrel 1/35-21, Nortrel 1/35-28, Nortrel 7/7/7, Ortho-Novum 1/35-21, Ortho-Novum 1/35-28, Ortho-Novum 10/11-21, Ortho-Novum 10/11-28, Ortho-Novum 7/14-21, Ortho-Novum 7/14-28, Ortho-Novum 7/7/7-21, Ortho-Novum 7/7/7-28, Ovcon-35, Ovcon-50, Philith, Pirmella 1/35, Pirmella 7/7/7, Tri-Norinyl 21-Day, Tri-Norinyl 28-Day, Vyfemla, Wera)
Ethinylestradiol and norethisterone acetate [and/or ferrous fumarate (Fe)] (Activella, Alyacen 1/35, Alyacen 7/7/7, Alyacen 777, Amabelz, Aranelle, Aurovela 1.5/30,[1] Aurovela 1/20,[2] Aurovela 24 Fe,[3] Aurovela Fe 1.5/30,[4] Aurovela Fe 1/20,[5] Aurovela Fe,[6] Aygestin, Balziva-21, Balziva-28, Blisovi 24 Fe,[7] Blisovi Fe 1.5/30,[8] Blisovi Fe 1/20,[9] Brevicon 21-Day, Brevicon 28-Day, Briellyn, Camila, Chabelina Fe,[10] Charlotte 24 Fe,[11] Combipatch, Cyclafem 0.5/35, Cyclafem 1/35, Cyclafem 7/7/7, Cyonanz, Dasetta 1/35, Dasetta 7/7/7, Errin, Estrostep 21,[12] Estrostep Fe,[13] Femcon Fe, Femhrt,[14] Finzala,[15] Fyavolv,[16] Gemmily,[17] Gencept 10/11-21, Gencept 10/11-28, Gildagia, Gildess 1.5/30,[18] Gildess 1/20,[19] Gildess 24 Fe,[20] Gildess Fe 1.5/30,[21] Gildess Fe 1/20,[22] Hailey 1.5/30,[23] Hailey 24 Fe,[24] Hailey Fe 1.5/30,[23] Hailey Fe 1/20,[25] Heather, Incassia, Jencycla, Jinteli,[26] Junel 1.5/30,[27] Junel 1/20, Junel 21,[28] Junel Fe 1.5/30,[27] Junel Fe 1/20,[29] Junel Fe 24,[30] Junel Fe 28,[28] Kaitlib Fe, Larin 1.5/30,[31] Larin 1/20,[32] Larin 24 Fe,[33] Larin Fe 1.5/30,[34] Larin Fe 1/20,[35] Leribane, Lo Larin Fe, Lo Loestrin Fe,[36] Lo Minastrin Fe, Lo-Blisovi Fe, Loestrin 21 1.5/30, Loestrin 21 1/20, Loestrin 21,[37] Loestrin 24 Fe,[38] Loestrin Fe 1.5/30, Loestrin Fe 1/20, Loestrin Fe 28,[37] Lomedia 24 Fe,[39] Lupaneta Pack, Melodetta 24 Fe,[40] Merzee,[41] Mibelas 24 Fe, Microgestin 1.5/30, Microgestin 1/20, Microgestin Fe 1.5/30, Microgestin Fe 1/20, Micronor, Minastrin 24 Fe, Modicon 21, Modicon 28, Myfembree, N.E.E. 1/35 21, N.E.E. 1/35 28, Nexesta Fe, Nor-Qd, Norcept-E 1/35 21, Norcept-E 1/35 28, Norethin 1/35E-21, Norethin 1/35E-28, Norethin 1/50M-21, Norethin 1/50M-28, Norinyl, Norinyl 1+35 21-Day, Norinyl 1+35 28-Day, Norinyl 1+50 21-Day, Norinyl 1+50 28-Day, Norinyl 1+80 21-Day, Norinyl 1+80 28-Day, Norlestrin 21 1/50, Norlestrin 21 2.5/50, Norlestrin 28 1/50, Norlestrin Fe 1/50, Norlestrin Fe 2.5/50, Norlutate, Norlutin, Norminest Fe, Norquest Fe, Nortrel 0.5/35-21, Nortrel 0.5/35-28, Nortrel 1/35-21, Nortrel 1/35-28, Nortrel 7/7/7, Nylia 1/35, Nylia 7/7/7, Oriahnn (Copackaged), Ortho-Novum 1/35-21, Ortho-Novum 1/35-28, Ortho-Novum 1/50 21, Ortho-Novum 1/50 28, Ortho-Novum 1/80 21, Ortho-Novum 1/80 28, Ortho-Novum 2-21, Ortho-Novum 7/7/7-21, Ortho-Novum 7/7/7-28, Ortho-Novum 7/14-21, Ortho-Novum 7/14-28, Ortho-Novum 10-21, Ortho-Novum 10/11-21, Ortho-Novum 10/11-28, Ovcon-35, Ovcon-50, Philith, Pirmella 1/35, Pirmella 7/7/7, Taytulla, Tri-Legest 21, Tri-Legest 21 , Tri-Legest Fe, Tri-Norinyl 21-Day, Tri-Norinyl 28-Day, Vyfemla, Wera)
Ethinylestradiol and norgestimate (Estarylla, Mili, Mono-Linyah, Ortho Cyclen-21, Ortho Cyclen-28, Ortho Tri-Cyclen, Ortho Tri-Cyclen 21, Ortho Tri-Cyclen 28, Ortho Tri-Cyclen Lo, Previfem, Sprintec, Tri Lo Sprintec, Tri-Estarylla, Tri-Linyah, Tri-Lo-Estarylla, Tri-Lo-Linyah, Tri-Mili, Tri-Previfem, Tri-Sprintec)
Ethinylestradiol and norgestrel (Cryselle, Elinest, Lo/Ovral, Lo/Ovral-28, Low-Ogestrel-21, Low-Ogestrel-28, Ogestrel 0.5/50-21, Ogestrel 0.5/50-28, Ovral, Ovral-28)
Mestranol and norethisterone (Norinyl 1+50 28-Day)
Transdermal patches
Vaginal rings
Combined injectable contraceptives
Estradiol cypionate and medroxyprogesterone acetate (Lunelle; 5 mg / 25 mg) was previously available in the U.S. but was discontinued.
Progestogen-only contraceptives
Progestogen-only pills
Norgestrel (Ovrette; 0.075 mg) was previously available in the U.S. but was discontinued.
Postcoital emergency contraceptive pills
Levonorgestrel (Athentia Next, Fallback Solo, Her Style, Opcicon One-Step, Plan B, Plan B One-Step) – 0.75 mg, 1.5 mg
Progestogen-only injectable contraceptives
Intrauterine devices
Levonorgestrel (Kyleena, Liletta, Mirena, Skyla) – 13.5 mg/device, 19.5 mg/device, 52 mg/deviceProgesterone (Progestasert; 38 mg/device) was previously available in the U.S. but was discontinued.
Subcutaneous implants
Etonogestrel (Implanon, Nexplanon) – 68 mg/implant
Levonorgestrel (Jadelle, Norplant, Norplant System in Plastic Container) – 36 mg/implant, 75 mg/implant
For other uses
Combined with estrogen
Oral pills
Estradiol/progesterone (TX-001HR), a combination of estradiol and progesterone in oil-filled capsules, is currently pending approval.[43]
Estradiol and norgestimate (Prefest; 1 mg / 90 μg) was previously available in the U.S. but was discontinued.
Transdermal patches
Progestogen-only
Oral pills
Medroxyprogesterone acetate (Amen, Curretab, Cycrin, Provera) – 2.5 mg, 5 mg, 10 mg
Megestrol acetate (Megace) – 20 mg, 40 mg – approved specifically for the treatment of breast and endometrial cancer [44] and for the treatment of anorexia , cachexia , and weight loss in patients with AIDS Tooltip acquired immunodeficiency syndrome [45]
Norethisterone acetate (Aygestin, Norlutate) – 5 mg
Progesterone (Prometrium) – 100 mg, 200 mg, 300 mgAtypical:
Danazol (Danocrine) – 50 mg, 100 mg, 200 mg – approved specifically for the treatment of endometriosis
Oral suspensions
Vaginal tablets
Vaginal gels
Intramuscular injectables
Miscellaneous
Norethisterone acetate and leuprorelin (Lupaneta Pack) – 5 mg norethisterone acetate oral pills, 3.75 mg/vial, 11.25 mg/vial leuprorelin for intramuscular injection – approved specifically for the treatment of painful endometriosis