Genetic studies on the Sinhalese is part of population genetics investigating the origins of the Sinhalese population.
All studies agree that there is a significant relationship between the Sinhalese and the Bengalis and South Indian Tamils, and that there is a significant genetic relationship between Sri Lankan Tamils and Sinhalese. This is also supported by a genetic distance study, which showed low differences in genetic distance between the Sinhalese and the Bengali, Tamil, and Keralite volunteers.[1]
Relationship to Bengalis
An Alupolymorphism analysis by Mastana S (2007) using Sinhalese, Tamil, Bengali, Gujarati (Patel), and Punjabi as parental populations found the following proportions of genetic contribution:[2]
Genetic distance analysis by Kirk (1976) found the Sinhalese to be closer to the Bengal than they are to populations in Gujarat or the Panjab.[4]
D1S80 allele frequency (a popular allele for genetic fingerprinting) is also similar between the Sinhalese and Bengalis, suggesting the two groups are closely related.[5]
The Sinhalese also have similar frequencies of the allele MTHFR 677T (13%) to West Bengalis (17%).[6][7]
A genetic admixture study by Kshatriya (1995) found the Sinhalese to have a higher contribution from Indian Tamils (69.86% +/- 0.61), compared with the Bengalis (25.41% +/- 0.51).[10]
Genetic distance analysis by Roychoudhury AK et al. (1985) suggested the Sinhalese are more closely related to South and West Indian populations, than the Bengalis.[11]
Genetic distance analysis by Kirk (1976) suggested the Sinhalese are closer to the Tamils and Keralites of South India, than they are to the populations in Gujarat or the Panjab.[4]
A 2023 study by Singh et al using higher resolution markers than previous studies found that there was higher gene flow from South India to the Sinhalese than from North India, with the Sinhalese sharing the highest Identity by descent with Tamils compared to the other Indian populations studied. The study also found heightened sharing with the Maratha of north western India which was lacking in Tamil and other South Indian populations, consistent with a trace of North Indian affiliation to the Sinhalese population. The total Sinhalese sample size used was 9 individuals.[12]
Relationship to North West Indians
An Alupolymorphism analysis by Mastana S (2007) found a minor North West Indian contribution (20-23%).[13]
Analysis of X chromosome STRs by Perera et al., (2011) showed that the Sinhalese, Sri Lankan Tamil, Moor and Indian Tamils of Sri Lanka, share affinities with the Bhil (an Indigenous group) of North West India.[14]
Relationship to other major ethnic groups in Sri Lanka
A study looking at genetic variation of the FUT2 gene in the Sinhalese and Sri Lankan Tamil population, found similar genetic backgrounds for both ethnic groups, with little genetic flow from other neighbouring Asian population groups.[15] Studies have also found no significant difference with regards to blood group, blood genetic markers (Saha, 1988) and single-nucleotide polymorphism between the Sinhalese and other ethnic groups in Sri Lanka.[16][17][18] Another study has also found "no significant genetic variation among the major ethnic groups in Sri Lanka".[19] This is further supported by a study which found very similar frequencies of alleles MTHFR 677T, F2 20210A & F5 1691A in Indian Tamil, Sinhalese, Sri Lankan Tamil, and Sri Lankan Moor populations.[7]
Relationship to East and Southeast Asians
Genetic studies show that the Sinhalese have received some genetic flow from neighboring populations in East Asia and Southeast Asia, such as from the ethnically diverse and disparate Tibeto-Burman peoples and Austro-Asiatic peoples,[20] which is due to their close genetic links to Northeast India.[21][22][23] A 1985 study conducted by Roychoudhury AK and Nei M, indicated the values of genetic distance showed that the Sinhalese people were slightly closer to Mongoloid populations due to gene exchange in the past.[11][24] In regards to comparisons of root and canal morphology of Sri Lankan mandibular molars, it showed that they were further away from Mongoloid populations.[25] Among haplogroups found in East Asian populations, a lower frequency of East Asian mtDNA haplogroup, G has been found among the populations of Sri Lanka alongside haplogroup D in conjunction with the main mtDNA haplogroup of Sri Lanka's ethnic groups, haplogroup M.[26] In regards to Y-DNA, Haplogroup C-M130 is found at low to moderate frequencies in Sri Lanka.[27]
Genetic markers of immunoglobulin among the Sinhalese show high frequencies of afb1b3 which has its origins in the Yunnan and Guangxi provinces of southern China.[28] It is also found at high frequencies among Odias, certain Nepali and Northeast Indian, southern Han Chinese, Southeast Asian and certain Austronesian populations of the Pacific Islands.[28] At a lower frequency, ab3st is also found among the Sinhalese and is generally found at higher frequencies among northern Han Chinese, Tibetan, Mongolian, Korean and Japanese populations.[28] The Transferrin TF*Dchi allele which is common among East Asian and Native American populations is also found among the Sinhalese.[11] HumDN1*4 and HumDN1*5 are the predominant DNase I genes among the Sinhalese and are also the predominant genes among southern Chinese ethnic groups and the Tamang people of Nepal.[29] A 1988 study conducted by N. Saha, showed the high GC*1F and low GC*1S frequencies among the Sinhalese are comparable to those of the Chinese, Japanese, Koreans, Thais, Malays, Vietnamese, Laotians and Tibetans.[30] A 1998 study conducted by D.E. Hawkey showed dental morphology of the Sinhalese is closely related to those of the Austro-Asiatic populations of East and Northeast India.[20]Hemoglobin E a variant of normal hemoglobin, which originated in and is prevalent among populations in Southeast Asia, is also common among the Sinhalese and can reach up to 40% in Sri Lanka.[31]
Haplogroup M represents the dispersal of modern humans around 60.000 years ago along the southern Asian coastline following a southern coastal route across Arabia and India to reach Australia short after.[35]
Haplogroup U7 is considered a West Eurasian–specific mtDNA haplogroup, believed to have originated in the Black Sea area approximately 30,000 years ago. In South Asia, U7 occurs in about 12% in Gujarat, while for the whole of India its frequency stays around 2%, and 5% in Pakistan. In the Vedda people of Sri Lanka it reaches its highest frequency of 13.33% (subclade U7a). It is speculated that large-scale immigration carried these mitochondrial haplogroups into India.[36]
Chaubey states that "considerable number of maternal lineages of Sri Lanka is shared with India, more precisely with southern part of India."[37]
References
^Kirk, R. L. (July 1976). "The legend of Prince Vijaya — a study of Sinhalese origins". American Journal of Physical Anthropology. 45 (1): 91–99. doi:10.1002/ajpa.1330450112.
^Perera, N., Galhena, G. and Ranawaka, G., 2021. X-chromosomal STR based genetic polymorphisms and demographic history of Sri Lankan ethnicities and their relationship with global populations. Scientific reports, 11(1), pp.1-12.
^ abKirk RL (July 1976). "The legend of Prince Vijaya – a study of Sinhalese origins". American Journal of Physical Anthropology. 45 (1): 91–99. doi:10.1002/ajpa.1330450112.
^Surinder Singh Papiha (1999). Genomic Diversity: Applications in Human Population Genetics. London: Springer. 7.
^ abDissanayake VH, Weerasekera LY, Gammulla CG, Jayasekara RW (October 2009). "Prevalence of genetic thrombophilic polymorphisms in the Sri Lankan population--implications for association study design and clinical genetic testing services". Experimental and Molecular Pathology. 87 (2): 159–62. doi:10.1016/j.yexmp.2009.07.002. PMID19591822.
^Kshatriya GK (December 1995). "Genetic affinities of Sri Lankan populations". Human Biology. American Association of Anthropological Genetics. 67 (6): 843–66. PMID8543296.
^ abcRoychoudhury AK, Nei M (1985). "Genetic relationships between Indians and their neighboring populations". Human Heredity. 35 (4): 201–6. doi:10.1159/000153545. PMID4029959.
^Prajjval Pratap Singh, Sachin Kumar, Nagarjuna Pasupuleti, Niraj Rai, Gyaneshwer Chaubey, R. Ranasinghe, "Reconstructing the population history of Sinhalese, the major ethnic group in Śrī Laṅkā," iScience, August 31, 2023, DOI: https://doi.org/10.1016/j.isci.2023.107797.
^Perera, N., Galhena, G. and Ranawaka, G., 2021. X-chromosomal STR based genetic polymorphisms and demographic history of Sri Lankan ethnicities and their relationship with global populations. Scientific reports, 11(1), pp.1-12.
^Soejima M, Koda Y (December 2005). "Denaturing high-performance liquid chromatography-based genotyping and genetic variation of FUT2 in Sri Lanka". Transfusion. 45 (12): 1934–9. doi:10.1111/j.1537-2995.2005.00651.x. PMID16371047. S2CID10401001.
^Saha N (1988). "Blood genetic markers in Sri Lankan populations--reappraisal of the legend of Prince Vijaya". American Journal of Physical Anthropology. 76 (2): 217–25. doi:10.1002/ajpa.1330760210. PMID3166342.
^Roberts DF, Creen CK, Abeyaratne KP (1972). "Blood Groups of the Sinhalese". Man. 7 (1): 122–127. doi:10.2307/2799860. JSTOR2799860.
^Illeperuma RJ, Mohotti SN, De Silva TM, Fernandopulle ND, Ratnasooriya WD (June 2009). "Genetic profile of 11 autosomal STR loci among the four major ethnic groups in Sri Lanka". Forensic Science International. Genetics. 3 (3): e105-6. doi:10.1016/j.fsigen.2008.10.002. PMID19414153.
^Soejima M, Koda Y (January 2007). "Population differences of two coding SNPs in pigmentation-related genes SLC24A5 and SLC45A2". International Journal of Legal Medicine. 121 (1): 36–9. doi:10.1007/s00414-006-0112-z. PMID16847698. S2CID11192076.
^Bhasin MK (4 September 2017). "Morphology to Molecular Anthropology: Castes and Tribes of India". International Journal of Human Genetics. 9 (3–4): 145–230. doi:10.1080/09723757.2009.11886070. S2CID53353581.
^Peiris R, Takahashi M, Sasaki K, Kanazawa E (July 2007). "Root and canal morphology of permanent mandibular molars in a Sri Lankan population". Odontology. 95 (1): 16–23. doi:10.1007/s10266-007-0074-8. PMID17660977. S2CID8504778.
^Fujihara J, Yasuda T, Iida R, Ueki M, Sano R, Kominato Y, et al. (July 2015). "Global analysis of genetic variations in a 56-bp variable number of tandem repeat polymorphisms within the human deoxyribonuclease I gene". Legal Medicine. 17 (4): 283–6. doi:10.1016/j.legalmed.2015.01.005. PMID25771153.
^Ranasinghe, Ruwandi; Tennekoon, Kamani H.; Karunanayake, Eric H.; Lembring, Maria; Allen, Marie (November 2015). "A study of genetic polymorphisms in mitochondrial DNA hypervariable regions I and II of the five major ethnic groups and Vedda population in Sri Lanka". Legal Medicine. 17 (6): 539–546. doi:10.1016/j.legalmed.2015.05.007. PMID26065620.
^Chaubey, G. Language isolates and their genetic identity: a commentary on mitochondrial DNA history of Sri Lankan ethnic people: their relations within the island and with the Indian subcontinental populations. J Hum Genet 59, 61–63 (2014). https://doi.org/10.1038/jhg.2013.122