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The Dasht-e Khash, also Dasht-e Khash or Dasht-e Khāsh. is a desert in Afghanistan's Nimruz Province. The desert is adjacent to the Dasht-e Margo. Located at 620 meters above sea level, it is among the five major deserts in Afghanistan, the other four being Dasht-e-Leili, Dasht-e Margo, Dasht-e Naomid, and Registan Desert.

31°49′59″N 62°30′0″E / 31.83306°N 62.50000°E / 31.83306; 62.50000