James E. Darnell
James E. Darnell receiving the 2002 National Medal of Science
Born (1930-09-09) September 9, 1930 (age 93)
CitizenshipUnited States
Alma mater
Known for
  • Original discovery of RNA processing in eukaryotes.
  • Determined how extracellular proteins (cytokines) stimulates nuclear gene expression.
AwardsAlbany Medical Center Prize (2012)[1]
Albert Lasker Special Achievement Award (2002)
National Medal of Science (2002)[2]
E.B. Wilson Medal (1998)
Canada Gairdner International Award (1986)[3]
Scientific career

James Edwin Darnell Jr. (born September 9, 1930, Columbus, Mississippi)[5] is an American biologist who made significant contributions to RNA processing and cytokine signaling and is author of the cell biology textbook Molecular Cell Biology.

In 2004, he was elected a foreign member of the Royal Swedish Academy of Sciences. He became a member of the American Philosophical Society in 2013.[6]

Since 2013, Darnell has been listed on the Advisory Council of the National Center for Science Education.[7]

He is married to Norwegian former model and dress shop owner Kristin Holby, known as "Clotilde", whose daughter Phoebe, a financial analyst, is married to businessman Divya Narendra.[8]



  1. ^ "'Towering Figures' in Cell Research to Share Albany Medical Center Prize". Albany Medical Center. Retrieved 11 February 2015.
  2. ^ "President's National Medal of Science, James E. Darnell". National Science Foundation. Retrieved 25 November 2014.
  3. ^ "Canada Gairdner International Award Recipient James E. Darnell MD". Gairdner Foundation. Retrieved 25 November 2014.
  4. ^ Strong, Colby (June 11, 1990). "People: James E. Darnell, Jr., Is Appointed Chief Academic Officer At Rockefeller University". The Scientist. 4 (12).
  5. ^ Laureates of the 2002 National Medal of Science
  6. ^ "APS Member History". search.amphilsoc.org. Retrieved 2021-03-17.
  7. ^ "Advisory Council". ncse.com. National Center for Science Education. Archived from the original on 2013-08-10. Retrieved 2018-10-30.
  8. ^ Seymour, Lesley Jane (29 July 2007). "Swap Those Jeans for a Dress, Soccer Mom". The New York Times.
  9. ^ National Science Foundation - The President's National Medal of Science